1741
KLINICKÁ341804301074588109168189242288347
FARMAKOLOGIE708804301074392139212266313373416475534555599
A13288043010753
FARMACIE1402804301074292139211266317337381
/18048043010757
Klin1880804301077091109157
Farmakol2057804301074278105179220258305325
Farm2402804301074178104179
2020;2601804301074386128171187
34(2):2807804301074489113156178193
63–693019804301074487133180223
/32618043010757
www.klinickafarmakologie.cz4568804301076513320121425327329234035839843647950254457164568672477179183988990895196610061045
681828026012657116
PŘEHLEDOVÉ341207012660124182256312369444520587645
ČLÁNKY1008207012660115187259327395
Vliv3413650106366785123
genetických48036501063769110142176194228264303336377
a872365010638
epigenetických9253650106316683122154195227261278313349388420462
faktorů140136501063068103137176212253
jako16693650106236297136
kovariátů182136501063372110146181199239267308
snášenlivosti214436501063273112146178219250268306346378411429
a2588365010638
léčebné26413650106306297129165207239
odpovědi289536501063979114155192224264281
na319236501063979
olanzapin328736501063870111152185227261279320
v3622365010637
terapii36733650106316399141175193210
psychotických389936501063266103136177218248266300336375408449
onemocnění436436501063880111166206242283315356374
dictors340554083385385109146168195
of5515540833757
poor6245540833977116138
treatment777554083234478110132190225263284
response1077554083215582121160198225260
in13525540831653
patients1422554083387193108143181203230
with1669554083506688126
schizophrenia1811554083275997112141178340654083397798132170186218
treated573654083254781113134168208
with800654083506688126
atypical942654083355791131146178211226
antipsychotics.1184654083357395110149176208240278316338353385413427
BMC16266540833994135
Psychiatry1776654083396598129167182214340754083224377
2018;4327540833569100131144
18:591754083346578
376.684754083346698111
8.3408530853653
Stahl408854083386093132147
SM.5718540833893107
Stahl’s694854083385993131147161186
Essential896854083386693128167189204237252
Psychopharmacology11648540834167100132171210250289321343402435468505521560600632
Cambridge18128540834679137177340954083213675114149
University504954083448297130164185212227250283
Press803954083355589116143
2013:9619540833468100130142
608.11189540833469105118
9.34010530853751
Citrome4081054083496690112152212249
L,67410540834055
McEvoy75410540835690125158198231
JP,10011054083347177
Todtenkopf109410540834278119143179219250290331352
MS,147110540835691104
McDonnell160010540835791138179219259296312329
D,194510540835567
Weiden34011540835791106145179218
PJ.5731154083365567
A656115408341
commentary71311540833168126184219258279312333367
on109611540833776
the11871154083226095
efficacy1298115408334537088120153185219
of153311540833756
olanzapine16051154083375386124153186225241279314
for19341154083195778
the3401254083226095
treatment4501254083224377109131189224262284
of74912540833756
schizophrenia:8211254083265896111140177217256277311349364396408
the12441254083226095
past,13541254083397299122135
present,15041254083396095121156194216229
and174812540833270109
future.187312540831857791173401354083215567
Neuropsychiatr42213540834580118139176216242275306344359391413435
Dis8721354083456187
Treat9741354083335084116138
2019;112713540833468100130143
15:12851354083356576
2559–2569.137613540833469101134171203238272306317
10.3401453085367085
Cabaleiro43814540834073112145160195210231269
T,72014540833241
Lopez‑Rodriguez77514540833168108143173195232270310331346385423458487
R,127514540833650
Ochoa133814540834780118156189
D,154014540834556
Roman161014540833573131164202
M,182514540835468
Novalbos1906145408345833401554083326581120159187
J,54215540833042
Abad‑Santos59915540834787120160182214247286308345372
F.98715540833744
Polymorphisms10471554083407793126185224245286325340366425451
influencing1514155408320587693131166205237252291330
olanzapine1860155408343599113034016540832862101116154189
metabolism54516540835792114147186225241256282340
and90016540833270109
adverse102416540833271104138159187221
effects12611654083345372107139164191
in146816540831452
healthy153516540833873105120143181211
subjects.176216540832663102118152185209237251
Human34017540834585145178218
Psychopharmacology‑Clinical57417540834269103136175215256297330352413447480519536575616650673718734749789805838872889
and147917540833878118
Experimental161317540833973114152174190250287326349383399
2013;34018540833468100130141
28:4971854083346880
205–214.59218540833468103139170202233245
11.3401953085366780
Chagraoui43619540834584117157179212251290306
A,75819540834761
Thibaut8351954083387894134167206229
F,108019540833844
Skiba11401954083386986126159
M,132019540835670
Thuillez140519540833979117133148164200230
C,165119540834559
Bourin172619540834180119141157195
M.194219540835670
5-HT2C34020540833456102136172212
receptors5672054083215588121161183220241269
in85120540831553
psychiatric9202054083386597129167182214236257273305
disorders:12412054083385379117139177212233260273
A1529205408341
review.15862054083215587103138189200
Progress1801205408335569313315418834021540832754
in41021540832160
Neuro‑Psychopharmacology49121540834682121143182206244272305338377417458497531553613647680718735774815848
&1352215408340
Biological14062154083365291108147188204237271287
Psychiatry170921540834269102135174190223246268303
2016;34022540833468100131143
66:4992254083347082
120–135.5962254083356499137167197230242
12.3402353085366883
Perry4372354083356890111145
PJ,5952354083355567
Sanger67523540833265103142177198
T,88623540833241
Beasley94023540833570102129144179210
C.116323540834053
Olanzapine12292354083476395133162196235250288323
plasma15652354083395587113171203
concentrations178123540833168106138172210340245408322437698113151189215
and56824540833270109
clinical690245408331476299114146179194
response9002454083185279118157195221256
in117124540831351
acutely123524540833163101124157173205
ill14552454083122742
schizophrenic15102454083275997112141178217256277311349364396
patients.1919245408338713402554083223772110131159173
J528255408324
Clin5672554083405570108
Psychopharmacol6912554083356193125163201241279312333391424456493509
1997;121525540833464100133142
17:13732554083346373
472–477.146225540833466100134171203238244
13.3402653085366883
Hiemke4362654083445994152182216
C,66526540834053
Bergemann7312654083367192130165223255293331
N,107626540834457
Clement11462654083405590148183221243
HW,1402265408344102112
Conca152726540834077115148180
A,172126540834155
Deckert178926540834580113143177199223
J,34027540832436
Domschke38927540834584142168200238268302
K,70427540833549
Eckermann7662754083336494128149207240277315
G,109427540834457
et116427540833456
al.12332754083324760
Consensus130627540833976115141176214240277303
Guidelines16222754083448297135170186201238273300
for19372754083165475
Therapeutic34028540833270104125157195229266288302333
Drug68528540834566103141
Monitoring83828540835390128142164200220235272310
in116328540831148
Neuropsychopharmacology:122328540834478115135171210236267298335372410448479499556588619655670707746777790
Update34029540834483122155176210
2017.56529540833569100130136
Pharmacopsychiatry71629540833573105126185217249286326353385417455470502523545579
2018,131029540833468100131144
51:14692954083356674
e1.15592954083346373
14.3403053085366984
Carrillo4403054083407394116131147162200
JA,6553054083256579
Herraiz75030540834479101122155171200
AG,9663054083418497
Ramos107930540833668126165191
SI,12863054083334760
Gervasini136230540834480101135168195210248263
G,164130540834457
Vizcaino17143054083365281113145161198237
S,196730540833245
Benitez34031540833671110125148182212
J.56831540832942
Role6253154083418096132
of77231540834362
the85031540832766101
smoking‑induced96731540833190128159176214254276293331371409441475515
cytochrome14983154083377096133166205226264323358
P450187231540834073106140
(CYP)1A23403254083195895131149180217253
and60632540833270109
polymorphic7293254083397793125184222244283322337369
CYP2D6111232540834077113147192227
in135532540831351
steady‑state14213254083244881113152184206233256289311345
concentration177932540833269107139173211340335408322437698113151190
of54533540834160
olanzapine.6213354083415789127157190229245283318330
Journal96633540832867105126165197212
of119433540834160
Clinical12743354083395570107123154187203
Psychopharmacology149233540833966981301682062452843163373964284604973403454083155393125
2003;48034540833468104137149
23:6443454083346980
119–127.7403454083346292129160190223229
15.3403553085366883
Bozikas43835540833574102118148181208
VP,6613554083357277
Papakosta75335540833567106139169206233256289
M,105735540835568
Niopas11403554083456098138171197
L,135235540833245
Karavatos14123554083356990123155188209246273
A,170035540834155
Mirtsou­17703554083557091116144182220242
‑Fidani3403654083215570109141179194
V.55036540833645
Smoking61136540833391129160176214253
impact87936540831674113146178202
on109736540833876
CYP1A2118936540834077114146184219
activity14243654083326589104137152175208
in164836540831553
a1717365408332
group17663654083385996134173
of195636540833756
patients3403754083397294110145183205233
with5943754083516789128
schizophrenia.73737540833264103118147185225264285320358374406419
European11723754083387596134174210242280
Neuropsychopharmacology14733754083458111914017821824527830934838642646549851934038540835790122159175213252284
2004;64038540833468104140152
14:8083854083346577
39–44.90038540833468105142179191
16.3403953085367086
Nozawa44739540834584112146197230
M,69839540835468
Ohnuma78739540834786124162221253
T,105639540833847
Matsubara112339540835588110138175215248269303
Y,144139540834149
Sakai150639540833771101135150
Y,167239540834049
Hatano17413954083457799132171209
T,196639540833847
Hanzawa34040540834476114144177228261
R,61640540834054
Shibata6864054083377590129162184217
N,92340540834558
et99640540833961
al.10734054083365265
The115340540833777112
relationship12804054083266075108129145183221247285300339
between163540540834379101154189224262
the191240540832765100
response3404154083215582120159198224259
of61441540833857
clinical6864154083324762100115147180195
symptoms89641540832659118157179216274300
and121241540833169109
plasma13364154083385487113171203
olanzapine15544154083385486124153187226241279314
concentration,18834154083326910734042540833165103125146179201216254292305
based6624254083387198133172
on85142540833776
pharmacogenetics.94342540833977109131189221254291330365403438460476508535549
Therapeutic150742540833473108129162202237275297313345
Drug186842540834567105144
Monitoring34043540835493131146169206227243281320
2008;67543540833468105140152
30:8434354083346881
35–40.94043540833467103140176188
17.3404453085366876
Bondolfi43344540833574112151189205223240
G,68944540834457
Morel76244540835593115149164
F,94344540833238
Crettol9974454083406195117141178194
SV,12074454083337079
Rachid130244540833568100138153192
F,151044540833238
Baumann156444540833669106164197235273
P,185344540833539
Eap190844540833366105
CB.3404554083417892
Increased4484554083206093115151184211248289
clozapine7534554083375393122157197214253289
plasma10584554083456296123183216
concentrations129045540833876116149184224246269303325342381421448
and175445540833878118
side18884554083324888125
effects3404654083345473107140164191
induced5474654083165493130162196236
by79946540833970
smoking88446540832885124154171209248
cessation11474654083336693120153175190228266
in142946540831653
21499465408334
CYP1A2155046540834077114146183219
genotyped17864654083387311114917120534047540833872111
patients.4624754083387091105139176196223236
Therapeutic71047540833270103124156194228264286301331
Drug105347540834565102140
Monitoring120547540835390128142163199220235271309
2005;152647540833366101134144
27:16824754083346575
539–543.17684754083346698134167201232244
18.3404853085366985
Gaedigk44048540834476111151166205235
A,68948540834155
Leeder75848540833266101141176197
S,96948540833245
Miller10284854083557085101135157
N,119948540834457
Hoffman127048540834583103122180213251
M,153548540835468
Lee161748540833165101
M,173248540835468
Phillips18144854083357388103118133172199
M,34049540835468
Pratt4244954083355588110134
V,57449540833644
et63449540833456
al.7064954083324760
Pharmacogene78249540833572104126184216249285325360398433
Variation12314954083356688103135157172210249
Consortium149549540834077116142180202226242279337
(PharmVar).1847495408319559212514634050540835792123144162173
ed.5285054083387891
Children’s6385054083407893108147168203241253278
Mercy93550540835590111142175
in112650540831856
Kansas119850540833872110136170196
City,14135054083405678112121
USA:155450540834475116130
Pharmacogene16995054083397710913018922125329034051540833873111146
Variation5015154083366788104136158173211249
Consortium76651540834077115141180201226241279337
(PharmVar)11185154083185491124145203238269290308
2019.144151540833569100131142
19.3405253085366982
Tay4375254083376596
JK,5485254083296579
Tan64352540833664102
CH,7655254083408497
Chong88252540834078116154194
SA,10915254083377892
Tan119852540833765103
EC.13165254083377891
Functional142252540833773111144168183221259292307
polymorphisms174452540834482981301892272493405354083387791117174200
of55353540833756
the6245354083195792
cytochrome7285354083316489125158195216253311345
P45010865354083356799133
1A2123253540833370106
(CYP1A2)13535354083165592128160196232250
gene161553540833873110145
and177353540833169107
prolonged189353540833860973405454083155289127160199
QTc55154540834677104
interval6705454083114869101122155187202
in88754540831148
schizophrenia.9475454083255793108136172210248268301338352383396
Prog13555454083345490129
Neuropsychopharmacol14955454083447811513517121023526729733437141044747849934055540835790122159175
Biol5305554083355189105
Psychiatry6505554083356194125163178210232254288
2007;95355540833468104137147
31:11155554083346574
1297–1302.12045554083346498131163194224259292304
20.3405653085377490
Yasar4465654083417299134156
U,62356540834557
Babaoglu69656540834276117151190231247286
MO,1004565408356105117
Balibey11385654083427692108148185218
H,137656540834659
Cetin145156540834782105121160
M,163356540835670
Lundgren171956540833776115156196218253293
S,34057540833346
Rane40157540834174112147
A,56457540834661
Bozkurt64057540834179108139177199223
A.87957540834661
Association95657540834674101139172188220242257296334
of130657540834362
the138457540832665100
cytochrome15005754083367095132165204225262321356
P450187257540834073106140
1A2*134058540833471107135168
F521585408332
polymorphism5685854083448399131190228250290328343369427
with10165854083506688127
clozapine11585854083365290118152191206244279
response14535854083266087126164203229264
in173358540831957
schizophrenic1806585408331631011161461833405954083397798132170186217
patients.5735954083387193108143181203231244
Faseb8325954083336289124163
Journal101059540832463101122161193208
2007;123459540833468104137146
21:13965954083346574
A196-A196.148559540834171101136160201231261297310
21.3406053085367082
Czerwensky43960540834071105126179214252278308342
F,79660540833440
Leucht85160540833367105137175197
S,106360540833447
Steimer11256054083345589104161196218
W.135960540835868
CYP1A2*1D144460540834077113146183219247280322
and178160540833371110
*1190660540832962
F1981605408332
polymorphisms3406154083408096129189229251292332348375434461
have81761540834478110146
a979615408337
significant10336154083324787126142161178211245284307
impact135661540832079120154187212
on158461540834483
olanzapine16836154083446094133163198238254293330
serum3406254083266182121178
concentrations.53462540833168106139172210232253286308323361400426440
Ther98962540833372107128
Drug113262540834667106145
Monit129262540835493131146169
2015;147662540833468100130141
37:16326254083346777
152–160.17246254083346497132162194229242
22.3406353085367288
Ghotbi44763540834482121142182197
R,66063540833953
Mannheimer73263540835487125163201236251309344365
B,111263540833952
Aklillu11836354083417188103118133171
E,136963540833650
Suda143463540833673112145
A,159863540834155
Bertilsson16686354083397496120136151177203242280
L,196463540833548
Eliasson340645408333486395121148186224
E,58064540833246
Osby64164540834774113144
U.80064540834455
Carriers8716454083407394115131166187214
of110164540833756
the11726454083226095
UGT1A4128264540834489123156194228
14215266454083346598
T>G163664540833269113
gene176464540833873111146
variant1925645408332653406554083213668106128
are4836554083365791
predisposed5936554083396094134149175214253279314354
to96265540832663
reduced10406554083245898135168201241
olanzapine12966554083415789127157190229245283318
exposure--an162965540833869109147174211233267290313345383
impact34066540831572111144177201
similar55666540832742100115130162183
to75566540832359
male83166540835790105140
gender98766540833873111150185206
or121066540833759
smoking128466540832785123154170208247
in154666540831654
schizophrenic16156654083276098113142179219257278312350365397
patients.3406754083397293109143181203231244
Eur6006754083326990
J705675408324
Clin7456754083405570108
Pharmacol86867540833573105126184217249286302
2010;118567540833468100132144
66:13456754083347082
465–474.144267540833471104141178210240253
23.3406853085367185
Mao44068540835486122
M,57768540835567
Skogh6596854083326197135171
E,84568540833345
Scordo9056854083326399119155192
MG,111268540835598110
Dahl123768540834576112126
ML.13786854083558598
Interindividual14906854083155272104124138175213226257272309345376390
variation18956854083326383973406954083325266103140
in49469540831249
olanzapine5556954083375182119147179217231267301
concentration86869540833167104134167203224244275295309346383
influenced1265695408313496582118152188219251290
by156769540833868
UGT1A4164769540834487120152188221
L48V18806954083316398132
polymorphism3407054083397690120177214234272309323348404
in75770540831147
serumand8157054083265979115172213250287
upstreamFMOpolymorphisms111270540833775100122142174205261303355401450487501531588625645683720734759815839
in196570540831147
cerebrospinal3407154083316483116154174210235273287323354368
fluid.721715408317347083121133
J868715408322
Clin9037154083405467104
Psychopharmacol10197154083356091121158195233270301321378409440475490
2012;15217154083346797126137
32:16707154083356677
287–289.17597154083346798129160192225234
24.3407253085367186
Bozina44172540833978106121159192
N,65272540834457
Kuzman72472540833976105164196234
MR,97772540835591105
Medved110072540835590129162196236
V,135172540833948
Jovanovic14157254083276698131169207239255287
N,172072540834558
Sertic17937254083367193117133165
J,197372540832840
Hotujac34073540834381102139154185216
L.56873540833144
Associations6257354083406793130162176208229243280318343
between9817354083387294146179214251
MDR1124473540835499134165
gene142273540833771108142
polymorphisms15767354083397692123180217238277315329355411437
and34074540833270109
schizophrenia4647454083275997112141179218257278312350365397
and87674540833371110
therapeutic10017454083226196117150189224262285300332
response13487454083225683121160199225260
to162374540832360
olanzapine16997454083375385123152186225240278313
in34075540831553
female40875540832155113146161196
schizophrenic6197554083296199114144181220259280314352367399
patients.10367554083397294109144182203231245
Journal129675540832765103124163195211
of152575540833756
Psychiatric15977554083386496128166181213235256272304
Research1916755408338733407654083266193114145183
2008;53976540833468104139152
42:7067654083346779
89–97.80076540833569106141174180
25.3407753085367286
Rao43977540833567105
VV,5577754083357483
Dahlheimer65277540834577115130167202216274308329
JL,9967754083215366
Bardgett10757754083356888126165199221245
ME,133277540835487100
Snyder14457754083326999137172192
AZ,16507754083418093
Finch17557754083324784116154
RA,19217754083357891
Sartorelli2140554083326586110146168201217231246
AC,2399554083407992
Piwnica‑Worms25035540833549100138153184217239296332353411437
D.29535540834556
Choroid30215540834077115136173188227
plexus3260554083395489120157183
epithelial3456554083337288110147182197212244259
expression372755408334652140654083396094121148163201239
of23956540833757
MDR1246865408354100136169
P265365408335
glycoprotein2704654083385385117154193215252274308323361
and30806540833371110
multidrug32066540835795110132148187208246285
resistance­350665408322568397124147179218250283306
‑associated2140754083215380106145177192224246280319
protein2478754083386097119153168206
contribute26997540833471110131153168207246268302
to30167540832562
the3093754083256398
blood‑cerebrospinal­3209754083395593132171194227261282316356377414441480496534566581603
‑fluid214085408321385591106143
drug‑permeability2295854083385895133155194229249306340371409424439453475508
barrier.2815854083387090111126160180190
Proc3017854083355591123
Natl3152854083437596111
Acad32758540834071102141
Sci3427854083326478
U351785408343
S357285408332
A361685408340
1999;3668854083346398132144
96:2140954083347082
3900–3905.22379540833568104140178210243279313325
26.21401053085367187
Boulton224510540833574112127150187225
DW,2487105408346103113
DeVane261710540834681116147185220
CL,28541054083407286
Liston2955105408333497598135173
HL,31461054083447690
Markowitz325310540835487108139176227243265296
JS.35641054083275872
In365110540831755
vitro37211054083345072214011540832158
P‑glycoprotein221311540833859100115147178215255277314336369385422
affinity2651115408334537188126141164198
for28641154083215980
atypical29601154083345690130145177210226
and320111540833573112
conventional332811540833471109141175213235250288326359374
antipsychotics.37171154083357321401254083223776103135167205243265280312340353
Life25091254083314766100
Sci26251254083326479
2002;272012540833468104137149
71:28851254083346675
163–169.29751254083346699136167198232243
27.21401353085367180
Tiwari223413540833349101133155170
AK,24181354083417791
Sodani252413540833271110142180195
K,273413540833549
Dai27981354083457792
CL,29051354083397185
Ashby300413540834169106146177
CR,31951354083407690
Chen329913540834078113151
ZS,34641354083387284
Chen356313540834077112150
ZS.37281354083387185
Revisiting214014540833570103118144159182197235274
the24291454083236297
ABCs254314540834076117145
of270514540833756
Multidrug277814540835492108130145184205244283
Resistance30771454083367198112139162195233265298
in339114540831654
Cancer346214540834072110143176197
Chemotherapy.367614540834078113214015540835999121161197219254294327337
Current249315540834785107130165204227
Pharmaceutical273615540834180114136196230263298337361377410444460
Biotechnology32121554083425897120155189229268308324364405438
2011;366615540834176109138147
12:21401654083346477
570–594.223216540833467100138172205240253
28.21401753085357186
Fardel22391754083326181119153168
O,241917540834657
Lecureur24881754083316597134154187224245
V,274517540833544
Guillouzo28011754083438095110124162199228264
A.307717540834155
The314417540833271105
P‑glycoprotein32611754083355595110141172208246267304325358373410
multidrug3683175408357941082140185408321367394131168
transporter.23231854083183971108133171208229253285305315
General265018540834377114148168200215
Pharmacology287618540833571102122179210241277292329367398
1996;32861854083346397131143
27:34401854083346675
1283–129135271854083336295128163193221254285
29.21401953085367285
Schinkel224119540833668106121159189223239
AH,24981954083418598
Wagenaar261419540835889128163201233265287
E,291619540833548
Mol298219540835593109
CAAM,310919540834083126182195
vanDeemter331919540833568106152187222280302336357
L.369119540833448
P­375419540833859
‑glycoprotein21402054083216177108140177216238275297331346384
in253920540831856
the26102054083256398
blood‑brain27272054083385492131171193233255288303341
barrier30862054083397293115130165186
of329120540833756
mice336620540835772104138
influences3519205408318567390128163201233267293
the21402154083226094
brain22472154083396093108146
penetration240621540833874112146169190223244260297336
and275421540833270109
pharmacological287621540833877109130188220252289305343382397429462477
activity33662154083326488103135151173207
of358621540833756
many365521540835789127157
drugs.21402254083385998137163176
Journal233222540832462100121160192208
of255522540833757
Clinical26272254083405570108123155188203
Investigation28452254083155384119146169184223255277292330369
1996;322922540833464100135147
97:33922254083346777
2517–2524.348422540833469100130162194228262293306
30.21402353085367287
Lankas224223540833670108138171198
GR,24602354083448094
Wise25742354083577399134
LD,27242354083368192
Cartwright28322354083447798123176198213252290312
ME,316423540835487100
Pippert32802354083405493133168189214
T,350923540833847
Umbenhauer3575235408344102141177215214024540833870107142164
Dr.23172454083456777
Placental24072454083365083115148186208241256
P‑glycoprotein26772454083355696112143175212251273310332366381419
deficiency31092454083387391108140155189228260293
enhances341524540833472111143181213247274
susceptibility37042454083246187214025540833165104126142181196211226249283
to243825540832561
chemically251525540833472107165180212245260275307
induced28382554083175594132164198237
birth3094255408338547599138
defects32502554083387392127159183211
in347625540831856
mice.355025540835873105139151
Reproductive37162554083387321402654083396097137175207231246279313
Toxicology24682654083336797113145182198236275307
1998;27912654083346499134146
12:29532654083346476
457–463.304526540833467100132169205239252
31.21402753085366981
Lin22342754083314784
YC,23312754083357386
Ellingrod2430275408333476277115154175212251
VL,26942754083356882
Bishop27882754083365177114152192
JR,29952754083225771
Miller30792754083547085100134155
DD.324727540834591102
The336227540833271106
relationship34832754083195268100122137174213239276291330
between21402854083387395147181215253
P‑glycoprotein24052854083355595110141172208246268304325358373410
(PGP)28302854083165194129147
polymorphisms29892854083387692123180218239278316330356412438
and343928540833269107
response35612854083185178116154192217252
to214029540832258
olanzapine22112954083375385123152185224239277312
treatment25382954083194174106128185220258280
in283329540831250
schizophrenia.28952954083265996111140177216255276310347362394407
Therapeutic331529540833372106127160199234272294310341
Drug366929540834567105144
Monitoring214030540835493131146169206227243281320
2006;247530540833468105140153
28:26433054083346880
668–672.273830540833570106143180213247260
32.21403153085367186
Kuzman224231540833976105164196234
MR,249531540835490104
Medved261831540835590129162196236
V,286931540833948
Bozina293231540833978106121159192
N,314231540834558
Grubisin321931540834365103142158184199237
J,347131540832840
Jovanovic35263154083286698131169207239255287
N,214032540834558
Sertic22133254083367192117132164
J.239232540832841
Association24523254083416895133166181213235250288327
study27943254083305391130162
of297132540834160
MDR13050325408355101137169
and323532540833573112
5-HT2C336332540833759105139175215
genetic359732540833873111146168183215
polymorphisms21403354083397894126185223245285324339365423450
and260533540833775115
antipsychotic‑induced27353354083377597113152179211243281320342357389408424462502539572606645
metabolic340133540835893115148188227243258290
disturbances3706335408344598521403454083226081121155193225259286
in244234540832058
female251534540832459117150165200
patients27313454083447799115149188210238
with29893454083516789128
schizophrenia.313234540833264103118147185225264285319358373405419
Pharmacogenomics356634540834178111132191224214035540833168108143181219277292324352
Journal250735540832463101122161193208
2011;273135540833468100127136
11:28823554083346270
35–44.296835540833467103140177189
33.21403653085367085
Jovanovic22403654083226091124162200231247278
N,253136540834557
Bozina260136540833573101116154186
N,280036540834457
Lovric286936540833269100122137169
M,305136540835467
Medved313136540835488128160194233
V,337736540833544
Jakovljevic34363654083225383120152168183217249265296
M,374536540835467
Peles21403754083356984119146
AM.230637540834197111
The243237540833777111
role25593754083256378113
of268837540834261
CYP2D6276437540834582119153197233
and301237540833775114
ABCB1314637540834177118153185
pharmacogenetics3346375408344821151361942262592963353704084432140385408321366895
in225038540831249
drug‑na23123854083385896135157195227
<2551385408342
ve260538540833165
patients26833854083387092107141178200227
with29223854083506688125
first‑episode3060385408317345481104123159198213238276315350
schizophrenia34223854083265895110139175214252273307344359390
treated21403954083224377109131165204
with23613954083516689127
risperidone.25033954083223864103139160176214253291326338
European28573954083347092129168204236274
Journal314639540832664102123162194210
of337339540833756
Clinical34463954083405570108123155188204
Pharmacology366739540833572104126214040540835790122159175213252284
2010;244040540833468100131144
66:25994054083357083
1109–1117.26974054083346293128166197224252281288
34.21404153085367388
al224341540833247
Mouaffak230541540835492130163182201235265
F,258441540833238
Oussama263741540834785111138171229261
K,291341540833549
Picard29774154083354981114135173
V,316541540833544
Bonhomme‑Faivre322441540833573112150188246304339362396426441473495529
L.376841540833145
Ultra‑Resistant21404254083456184106140163201237265281308331365404427
Schizophrenia258342540833871111126156195235275297332371387420
Is301942540832047
Not308842540834585107
Associated321142540834776104143177192225248283323
With35564254083587598138
the371042540832766102
Multidrug‑Resistant214043540835593108131147186207246285307345380407422449472505543565
Transporter27214354083385588127153192232253278312334
13070435408340
(MDR1)312543540832478125161194208
Gene335443540834480118153
rs104564235234354083265384115152185220256289
Variant.21404454083366788104136174195208
Journal236444540832462100122160192208
of258744540833757
Clinical26594454083405570108123155188203
Psychopharmacology28784454083356193125163201241279312333391424456493509547586618
2011;351244540833468100127136
31:36634454083346574
2.375244540833447
35.21404553085367186
Lee223945540833166101
ST,23544554083326675
Ryu244345540833568106
S,256345540833345
Kim262245540833551109
SR,27444554083336882
KimMJ,283945540833552109178203215
Kim306845540833551109
S,319145540833245
Kim324945540833552109
JW,33744554083228090
Lee347845540833165101
SY,35924554083336977
et368345540833356
al.37524554083324860
Association21404654083416895133165180212234249287325
study24784654083264986125157
of264846540833756
27271746540833467
annotated279746540833169107145167199221254294
genes310346540833873111146172
for32914654083155374
clozapine33784654083314684112146185200238272
pharmacogenetics:366346540833977109130214047540835789121158198232270305327342374402414
validation2567475408332648095133165187202240278
of285847540833756
preexisting29274754083396094130161176202225241278317
studies32574754083264987126141175202
and347247540833270108
identification359647540831251851231451601771942140485408331638498135173
of232548540833655
a2392485408331
new243548540833771121
candidate256848540833163100138153191222243276
gene,285648540833771108142154
ABCB1,302248540834075115149180189
for32254854083165273
treatment33134854083183972103124181215252273
response.3601485408317517711515219021404954083266173
J2229495408324
Clin22684954083405570108
Psychopharmacol23914954083356294126164202242280312334392424457493509
2012;291649540833468100130142
32:30734954083346780
441–448.316849540833471101134171208244257
36.21405053085367286
Saiz‑Rodríguez22385054083326579108128165202241262277315352386415
M,266450540835568
Belmonte27435054083367085142180217238271
C,302650540834052
Román309050540833573130162199
M,330150540835567
Ochoa338050540834779116154186
D,357850540834555
Jiang­36455054083243970107146167
‑Zheng21405154083215693128165203
C,235951540834052
Koller24275154083357287101135156
D,259851540834656
Mejía267051540835488103117149
G,283451540834457
et290651540833456
al.29785154083314658
Effect30525154083335170104136159
of322751540833755
ABCB1329851540834176116151182
C3435T349651540834075109141173207
Polymorphism371951540833571214052540831546104141162201239254279336
on249252540833775
Pharmacokinetics258352540833572103124182213245281311326364398420434465492
of309152540833856
Antipsychotics31635254083417999114152178210241278316337352383410
and358852540833370108
Antidepressants.37125254083417921405354083213673107145166199225250282319339366379
Basic25305354083356792106137
Clin26785354083405468105
Pharmacol279453540833571102122179211242277292
Toxicol30985354083326594108139175190
2018;32995354083346798128139
123:34505354083346296106
474–485.35685354083336494130166200233244
37.21405453085366978
Tovilla‑Zarate22315454083326697112127142174196231263284316338371
C,261454540834052
Vargas26795454083356686124156182
I,287654540831224
Hernandez29125454083447899137169206245279308
S,323254540833245
Fresan32895454083325285111144181
A,348354540834054
Aguilar354954540834178115130145177197
A,375954540834054
Escamilla21405554083336092125183198213229261
R,241655540833650
Saracco24815554083336687120152183220
R,271655540833549
et278155540833456
al.28535554083324760
Association29285554083416996134167182214236251289327
study32715554083264987126158
between34455554083387496149184219257
the37175554083226095
MDR12140565408354100137169
gene232256540833873111146
and248156540833270109
clinical26035654083314762100115147180195
characteristics281156540833169102123156188212246267283309332347379407
in323356540831250
schizophrenia.32995654083245694109138175215253274308347362394407
Revista3719565408335702140575408332477397129
Brasileira22855754083355689116131146181196217250
De255057540834681
Psiquiatria26465754083366277115153168200222243259291
2014;295257540833469100131143
36:31115754083346881
227–232.320757540833469102134166201233246
38.21405853085367084
PanJ,HanJ,WuJ,HuangH,YuQ,ShengL.MDR1SingleNucleotidePolymorphismG2677T/AandHaplotypeAreCorrelated22345854083356510113514519822926529930937641044445450854457461064770171275679084685890093696910051042108310951158120212371267130913221358139514091442149615311562214059540831548851051191561892342692833133704074274655015155395956486817137447778118318669089449811035106611031117115411741206124412781329134813811430146614851506153815521582160316351672
withResponsetoDocetaxel‑CisplatinChemotherapy21406054083506384120164197222258295331355388419454508544574606626657686718732752793806830867881911930944979102810641096115211881208124412771296132713631393
inPatients35466054083104690120140153185221241266
with21406154083516586123
Non‑Small‑Cell227561540834582119140170226257271285305347379393407
Lung269561540833167103141
Cancer.284861540834072108139171191200
Respiration30616154083356994132146166197217231268305
2009;337961540833466101135146
78:35386154083346677
49–55.362761540833566102135166177
39.21406253085367185
Fernandes22406254083387293132164202241276303
B,255862540834153
Steiner26276254083375892107145180202
J,284462540832941
Berk29016254083407596127
M,304962540835467
Molendijk313762540835493109144182221236251281
M,343962540835468
Gonzalez­352762540834482121150184199234264285
‑Pinto21406354083215974113135173
A,232963540834762
Turck24066354083397395127158
C,258063540834659
Nardin266063540834679101140155194
P,287063540834146
et293263540834063
al.30116354083375367
Peripheral30946354083417597113153193229250284300
brain‑derived341063540834567101116155178220255277293327362402
neurotrophic214064540833772109130167189210247286324339371
factor25266454083164981105141162
in270464540831249
schizophrenia27666454083265895110139176215253274308346361392
and317164540833269108
the32946454083195792
role34016454083185570105
of351964540833756
antipsychotics:35876454083327091106145171203214065540833169107129145177204217
meta‑analysis237065540835792114147169202240272287319346361387
and277065540833270109
implications.289465540831270109125140172205227242280318345358
Molecular326565540835593109144176214229262283
Psychiatry35616554083356194125163178210232214066540832155
2015;221066540833468100130141
20:23666654083346881
1108–1119.24636654083346293129166196224252282293
40.21406753085367489
Můj224367540835492107
případ23646754083396076115148187
–2565675408335
Je261667540832358
kyselina26886754083306491126141156194226
acetylsalicylová29296754083316497120153169195228244259291324340378410443
v3387675408331
každé34336754083296392130165
tabletě36136754083215493109144166200
stejná?2140685408326488095132163187
Bulletin23386854083357286100134155170207
Sdružení25566854083327090127156188225239
praktických28076854083385991120143158189218250281318
lékařů31396854083124575107127164
ČR331568540833973
2015;34006854083336697126136
25:35486854083336777
57–58.36376854083336697130163175
41.21406953085366981
Huang223569540834482114152191
E,244169540833245
Hettige250169540834479101125141180214
NC,27306954083458598
Zai28436954083387186
G,294369540834457
Tomasi301569540833266124157183198
J,322969540832335
Huang327869540834482114152191
J,348569540832335
Zai35346954083387186
CC,36356954083407891
Pivac37406954083355021407054083326597
N,225670540834558
et232970540833860
al.24057054083355164
BDNF248470540834086131164
Val66Met26637054083407187122158212247270
polymorphism29487054083438298129188226248288326341367425
and338870540833674113
clinical35177054083355065103118150183198
response373170540832458214071540832664102140165200
to235571540831855
antipsychotic24227154083316990104143169201232269306328343374
treatment28117154083193973104125182217254275
in310171540831249
schizophrenia31627154083265895109138174213251272305342357388
and356371540833168106
schizoaffective3682715408326579410921407254083286598118137171204228243276310
disorder24647254083385379118139177212234
patients:27117254083397294109144182203231244
a2968725408332
meta‑analysis.301472540835792115147170202240272288320347361388401
Pharmacogenomics342972540833572105126184217249286325360214073540833876134149181209
J2364735408324
2019;240473540833468100130143
19:25627354083346477
269–276.265573540833468101139170203235249
42.21407453085377288
Zai22447454083447893
G,235874540834559
Zai24337454083447893
C,254274540834659
Chowdhury261774540834785125177216255294315350
N,298874540834659
Tiwari306374540833956109142164180
A,326474540834256
Souza333674540833978117147181
R,353374540834256
Lieberman36057454083375389129165187214075540835890128
J,228375540832941
Meltzer234375540835590105127158192213
H,257575540834557
et264775540833961
al.27237554083365164
The280275540833777111
role29287554083266378113
of305675540834261
brain‑derived31377554083396093107145168208243264279311345385
neurotrophic35377554083427711513517319421525221407654083397792123
factor22787654083235688112149170
(BDNF)246376540832358104149182202
gene267976540834378116150
variants28447654083376990105137175196223
in308276540831957
antipsychotic31547654083367495110149175207238276314335350382
response35517654083255985124163201227261
and214077540833270108
antipsychotic‑induced22637754083377495110149175207238276314335350382400415453492529560594633
weight291577540835185100138176197
gain.31277754083437589127139
Progress32817754083406097136157191217243
in353977540831957
Neuro­361577540834580117138175198
‑Psychopharmacology3940554083215681112142179215253290321341398429459495510546584615
&456555408339
Biological4614554083344985100136174188219250264
Psychiatry4889554083356091121157171202222242275
2012;5175554083346697125136
39:5322554083346678
96–101.54105540833468104134164194202
43.3940653085367186
Abdolmaleky40396540834180120158174232264279314344378
HM,443065408345100113
Faraone4556654083326283116154193228
SV,4797654083326978
Glatt4888654083435992113138
SJ,5039654083325769
Tsuang5121654083325492124162201
MT.5335654083548897
Meta­54456540835590112145167
‑analysis3940754083215391123139171198212239
of41947540834161
association4270754083366389127160175207229244282321
between46067540834379101154188224262
the4883754083266499
T102C49987540833670101134174
polymorphism5187754083438298130188227248288327342368425
of39408540833757
the4012854083205893
5HT2a41198540833477111147179
receptor4313854083195386120159181218240
gene45668540833873111146
and47268540833270109
schizophrenia.4850854083255795110139176216254276310348363395408
Schizophrenia527285408332641021181471842232622833173940954083385385
Research4040954083357097132164185216254
2004;43099540833569105141153
67:4477954083346777
53–62.45709540833467103140174186
44.39401053085367489
Myers404210540835485119140167
RL,42221054083356780
Airey43151054083415676110141
DC,44691054083458699
Manier458010540835487124139173194
DH,478710540834589102
Shelton490210540833269104119141178216
RC,51311054083357588
Sanders‑Bush523210540833264102141175196223243280318344381
E.394011540833346
Polymorphisms39991154083357288120178217238278316331358415442
in445611540831250
the45221154083195792
regulatory46301154083185292129145177199236257291
region49371154083185292107145183
of513411540833756
the52061154083195792
human531111540833876133166204
serotonin55301154083245939401254083215880117155170208
5-HT2A416312540833961107141177219
receptor43971254083255992125164187224245
gene465712540834378116151
(HTR2A)482312540832367101138174216235
influence5073125408319577592129164202234268
gene535612540834377116151
expression.55221254083387039401354083396094121148163201239252
Biological42081354083355088104142182197229262277
Psychiatry45001354083366294126164179211233254288
2007;480313540833569105137147
61:49661354083346472
167–173.50541354083346598130161191225237
45.39401453085367186
Davies404214540834578109125160186
MA,424414540835597111
Conley437114540834077115131166197
Y,458414540833644
Roth46441454083357495134
BL.47941454083356781
Functional489114540833269107139163178216255287302
SNPs521014540833276112138
in536414540831553
Genes543314540834479117152179
Encoding394015540833370103139179194232271
the42261554083236196
5-HT2A433915540833456102136172214
Receptor456915540833671103137176198235257
Modify484215540835593133148167202
the50591554083236196
Affinity5171155408341607795133148171204
and539115540833371110
Potency55171554083357239401654083225593125158
of411016540833857
Several41791654083336799133154187202
Atypical43941654083416295135150182214229
Antipsychotic463616540834179100115154180213244281319341356388
Drugs.503616540834667105144170183
Biological52321654083355088103141180195227260275
Research55191654083367039401754083266193114145183
for41391754083185577
Nursing423117540834583104131146184223
2011;446917540833469100128136
13:46211754083346475
55–60.471117540833467103141176189
46.39401853085367388
Gu404118540834381
L,413418540833145
Long419118540833168106145
JX,43511854083215972
Yan443518540833564102
Y,454918540833543
Chen460518540833977111149
Q,476618540834760
Pan483918540833466103
RD,49551854083358191
Xie50591854083385286
XF,51581854083387076
Mao524618540835486124
XX,53821854083387891
et548518540833456
al.55531854083324759
HTR2A1438A/G394019540834579117153196226258291326368396440
polymorphism439519540834584101133192231254294333349375434
influences4844195408321597794132168207239274301
the516119540832766101
risk5278195408326426999
of539319540834363
schizophrenia547119540833265103119394020540832865105144165199237252284
but423920540834381104
not435820540834180102
bipolar44752054083435897136152184205
disorder46962054083425783121143181216237
or494820540834263
major503120540835789105143164
depressive521120540834277116137171198225240272306
disorder:55332054083425739402154083266586125160181195
A4150215408346
meta‑analysis.421721540835792115148170203241273289321348363389403
Journal463521540832968106127166199214
of486421540834362
Neuroscience494721540834580118139176203236251286324356390
Research535221540834176103138170191222261
2013;394022540833468100130141
91:40972254083346674
623–633.418722540833467102138176209242255
47.39402353085367079
Joober403423540832563102142177198
R,424823540833649
Benkelfat431323540833671109139173189208241263
C,459223540834053
Brisebois4661235408335567298133172211227253
K,492923540833550
Toulouse499523540833266104120158196222257
A,526823540834155
Turecki53392354083336687121154184200
G,555523540834457
Lal39402454083316479
S,403224540833244
BloomD,40892454083355088126183241251
et435324540833355
al.44212454083314659
T102C44922454083326596129168
polymorphism46722454083397792124182219240280318332358415
in510224540831249
the51662454083195791
5HT2A527024540833376110145186
gene546924540833772109144
and394025540833169107
schizophrenia:40592554083265895110138175214251272305343357389401
relation4475255408317516698119134171209
to469925540831855
phenotype476625540833876110148185207240279314
and509225540833269107
drug52122554083375895134
response53612554083175177115153191217251
variability.39402654083326586101133173188203218241274284
J4240265408324
Psychiatry42792654083356294126164179211232254288
Neurosci458226540834580118139176203235250
1999;484726540833565100135148
24:50112654083346678
141–146.51042654083346596128159190226240
48.39402753085367490
Chen404527540834078113151
RYL,421127540833671103117
Sham434327540833371103161
P,451927540833540
Chen457427540834078113151
EYH,474027540833370115128
Li488327540833247
T,494527540833342
Cheung500227540834078113151189228
EFC,524527540833365105118
Hui53792754083448197
TCK,549127540833271107121
Kwok394028540833687126158
CL,41142854083478094
et422428540834164
al.43042854083385568
No439428540834686
association44962854083386693133167183216239255295334
between484728540834582105160196233272
T102C513528540833974107141182
polymorphism53332854083468610313619623625939402954083397792118176
of413429540833756
serotonin-242062954083286384122143180219234272294325
Areceptor45432954083416397129163202224261283
gene484429540833873111146
and500529540833472111
clinical51322954083334863101116148181197
phenotypes534629540833977112151189211244394030540833974101
of405930540833756
Chinese41333054083397792130165192227
schizophrenic43753054083296199114143180220258280314352367399
patients.47913054083397294109144182203231245
Psychiatry50533054083356194125163179211232254288
Research53583054083367197132164185216254
2001;394031540833468104136144
105:41003154083346599110
175–185.42263154083346396132163194228240
49.39403253085357082
Hawi403432540834374124138
Z,418432540833749
Myakishev424532540835384116145160185222256287
MV,45433254083548997
Straub46513254083325273105141179
RE,48423254083346779
ONeill493332540834690124138153167
A,511232540834053
Kendler517732540833467104142156190210
KS,53993254083346880
Walsh549032540835687101394033540832664
D,401933540834556
Gill4090335408343597489
M.419433540835468
No427733540834583
association43753354083325885123156171203225240278316
or470633540833859
linkage4780335408315306898131170205
between50003354083397497150184219258
the52733354083215994
5-HT2a/538233540833456102136172204230
T102C394034540833368100134176
polymorphism413234540834585101134195234257298337353380440
and458834540833877117
schizophrenia472134540833266105121151189230270292327366382415
in515234540832160
Irish5228345408321425986125
families.536934540832459118134150166202229244
American394035540834199134155171203236274
Journal422935540832462101122160193208
of445235540833857
Medical452435540835590129144176209225
Genetics476435540834479117152175190222249
1997;50293554083346499132142
74:51863554083356577
370–373.527835540833567100138170202236249
50.39403653085367287
Arranz40423654083416284117155184
MJ,42413654083548092
Collier43483654083407793108123158179
DA,454136540834685100
Munro465536540835592130152189
J,485936540832436
Sham490936540833371103161
P,508436540833640
Kirov51393654083355172109141
G,529536540834457
Sodhi536736540833271110148163
M,554536540835468
Roberts394037540833573113148169194221
G,417437540834457
et424437540833456
al.43133754083314759
Analysis438537540834179111127158185200226
of462437540833756
a4693375408331
structural47373754083264971109141165202223256271
polymorphism50213754083397893125183221243282321336362419
in545537540831350
the55203754083205892
5-HT2A394038540833456102136171213
receptor41693854083185285118157179216238
and442038540833169108
clinical4541385408331476299114146179194
response47513854083185279118156195221256
to502238540831956
clozapine.50913854083314785113146185201239274286
Neuroscience53903854083447911713817520239403954083314681119151185
Letters41403954083326688112146167195
1996;435039540833464100135147
217:45133954083346595105
177–178.46333954083346498131161191224238
51.39404053085366981
Arranz40334054083406183115152181
MJ,42264054083548091
Munro433040540835391128149185
J,453040540832133
Birkett45754054083355071101134156180
J,477040540832133
Bolonna48154054083357388126163201232
A,506040540834054
Mancama512640540835486123155187244276
D,541440540834556
Sodhi548240540833270108394041540833853
M,400641540835468
Lesch40874154083316592124162
KP,42624154083357276
et435141540833457
al.44214154083314760
Pharmacogenetic449441540833572105126184217249286325360398433455471503
prediction50104154083386094134149181205220258297
of532041540833756
clozapine53894154083314785113146186201394042540833873
response.40284254083205581120159198224259271
Lancet431442540833265103135169191
2000;452142540833468104140153
355:46904254083346799110
1615–1616.48154254083356696126162193224255286299
52.39404353085377287
Saiz40424354083376984113
PA,41694354083407791
Garcia‑Portilla42784354083457798128143174196233269290315329344358390
MP,46864354083569295
Arango48004354083426295133172210
C,502843540834153
Morales510043540835694115147162197223
B,533843540834052
Alvarez54084354083425789122142176205
V,394044540833745
Coto40044454083417899136
E,415544540833850
Fernandez42204454083387292131164202241276305
JM,45404454083298597
et465244540833961
al.47284454083375264
Association48114454083427096134167182214235250288327
study51524454083315492132163
of533444540833958
serotonin5406445408331668712514618339404554083385290
24044455408339
Areceptor40934554083426396129162201222259280
(5-HT2A)43874554083235677123157192234252
and465345540833774113
serotonin47804554083316686123144181219233271
transporter50654554083264779117143181220241265298318
(5-HTT)53984554083235677123156193214
gene394046540833872109143
polymorphisms41014654083387691122179216237275313327351408433
with45524654083516586124
schizophrenia.46904654083306198111139175214251271304341355386398
Progress51024654083395894133153186211237
in535346540831855
neuro­542646540833871108128164186
‑psychopharmacology&biologicalpsychiatry2007;31:741–745.394047540832159841141441802162542903203403964264574925065425796106577047187547688048428558859169309781003103310631099111211421162118212141257129013241354136314061435144214851514154215731603163116621673
53.39404853085367186
Souza404148540833271109138172
RP,42284854083357176
de431948540833873
Luca440748540833168100133
V,455548540833645
Meltzer461548540835489105127158192213
HY,48434854083448088
Lieberman49464854083324782121157178236269307
JA,52684854083246478
Kennedy536148540833569107145180220252
JL.39404954083245670
Influence4025495408315537087125160198230264
of430449540833756
serotonin43764954083256082119141178216231269
34660495408334
Aand470749540834174112151
34873495408334
B4919495408335
receptor49704954083205487121160182219240
genes522649540833873111146172
on541449540833775
clozapine55044954083324785394050540832862101116154189
treatment41455054083254680112134192227265287
response44475054083245885124163202228263
in472550540831856
schizophrenia.479750540832962100115144181221259280314352368400413
Pharmacogenetics52255054083397610913018822125329032936439405154083387395110142170
and412551540833270109
Genomics424951540834479117156214229261289
2010;455351540833468100132144
20:47135154083346881
274–276.48095154083356898135167200232245
54.39405253085367388
McMahon404652540835487142175213251289
F,435152540833541
Buervenich440752540833876111132167201239254286324
S,474652540833548
Charney481252540834078110131170205236
D,506652540834657
Lipsky51385254083344988115145179
R,533252540833852
Rush539952540833876102140
A,555752540834155
Wilson39405354083577489115153191
A,414653540834155
Sorant42165354083327092125163184
A,441553540834155
et448553540833356
al.45555354083324760
Variation46305354083356788103135157173210249
in489453540831452
the49615354083215994
gene507053540833873111146
encoding523053540833472104141181196234273
the55185354083215994
serotonin39405454083266182119141178217232270
24223545408334
Areceptor42695454083416296129162202224260282
is456654540831339
associated46185454083325885123155171203224258297
with49285454083516789127
outcome50685454083377598129166224259
of534054540833756
antidepressant5409545408332709210714618039405554083396195122149182221243
treatment.41985554083274983115137196231270291305
American4518555408347105140162178210243282
Journal481555540833068107128167200215
of504655540834262
Human512855540834583141174212
Genetics536155540834480118153176191224251
2006;394056540833468104140152
78:41085654083346780
804–814.420356540833469106143179211242255
55.39405753085367185
Laika40405754083326681111145
B,420157540833548
Leucht426457540833266104136174196
S,447657540833245
Heres453757540834479100134161
S,471457540833346
Schneider477657540833264102140175190229264285
H,507857540834456
Steimer51515754083325387102160195216
W.538357540835767
Pharmacogenetics546757540833572104126394058540835688119155193227264298319334365391
and434358540833168106
olanzapine44615854083375283120148181219233270304
treatment:47805854083183972103124180214251272285
CYP1A2(star)1507658540834076111143179213230255277309329346376
F5463585408332
and550658540833269106
serotonergic39405954083266080116138173211245265302317348
polymorphisms43005954083387691122179216237276313328353409435
influence4750595408311486582118152189220253
therapeutic50185954083185589110142180215251273288319
outcome.53495954083367495125161218252264
Pharmacogenomics394060540833573105126184217249286325360398437495510542570
Journal452560540832462101122160193208
2010;474860540833469100132145
10:49086054083346679
20–29.500260540833468106138172183
56.39406153085367287
Li404061540833146
J,410161540832234
Hashimoto414761540834476102140154211249271307
H,446761540834456
Meltzer453661540835489104126156190211
HY.47606154083437987
Association48606154083416894132164179211232247285323
of519561540833756
Serotonin52646154083326788125146183221235273
2c554961540833464
Receptor394062540833569101134173194231252
Polymorphisms42046254083357186117175212233272310325350407433
With46496254083577394132
Antipsychotic47936254083417899114152179210241279316337352384
Drug518962540834566103142
Response53436254083356995134172209235269
in394063540831553
Schizophrenia.400863540833265103118147184224262283317355370402416
Front44396354083325289128149
Psychiatry46046354083356194125163178210232253287
2019;490763540833468100130143
10:50656354083346679
58.51596354083346882
57.39406453085367180
Wallace403864540835789104119151184217
TJ,42716454083345567
Zai43566454083377086
CC,44596454083407891
Brandl45676454083365790128167182
EJ,47656454083346173
Müller485564540835593108123158179
DJ.50526454083456780
Role51496454083357490124
of529164540833756
5-HT(2C)536364540833658104138156190230250
receptor39406554083205486119157179215236
gene418865540833872110144
variants4344655408331648499131168189216
in457565540831249
antipsychotic‑induced46366554083326990105143169201232269307328343374392408445483520552585623
weight52726554083508398136173194
gain.54796554083376984121133
Pharmgenomics394066540833573105126184224258297335393408440468
Pers44236654083356990117
Med455666540835489129
2011;470066540833468100128136
4:485166540833446
83–93.491366540833468104139172184
58.39406753085367287
Huang404067540834481113151189
XF,42426754083387076
Tan43316754083326097
YY,44416754083357381
Huang453567540834481113151189
X,473767540833851
Wang480167540835788125164
Q.497867540834658
Effect50486754083335270104137161
of522167540833756
chronic52906754083316989126164179211
treatment55166754083194074394068540833254112147185206
with41666854083506688127
clozapine43086854083355189117150190205243278
and460168540833674113
haloperidol47306854083417489127167202224239278316332
on507868540834179
5-HT2A517368540833860106140176218
and540668540833674113
2C553468540833978
receptor39406954083205486120158180217238
mRNA419169540835692137178
expression438269540833364103125158185211226263301
in469869540831250
the47636954083195691
rat48696954083185172
brain.49546954083385992107144157
Neuroscience512469540834479116137174200232247281319350384
Research55206954083357039407054083266193114145183
2007;413970540833468104137146
59:43017054083346679
314–321.43957054083356697134166199230240
59.39407153085367084
Padin403771540833567106121159
JF,42117154083225460
Rodriguez428471540833574113134150188226261290
MA,458771540835496110
Dominguez471071540834584142157195233271306335
E,505871540833246
Dopeso‑Reyes511671540834684124159186224247284319351385412
IG,55437154083125670
Buceta394072540833573105139161194
M,414972540835468
Cano423272540833972110149
E,439572540833346
Sotelo44567254083327193126142180
E,465172540833246
et471172540833457
al.47827254083324860
Parallel48577254083356788121137152187202
regulation50757254083205493131146178200216254292
by538272540833870
olanzapine54667254083385486124394073540832862101116154189
of414573540834161
the42217354083266499
patterns43357354083437698123156178216242
of459373540834161
expression466973540833870110131165192219233271310
of499473540834261
5-HT2A507073540833961107141177219
and530473540833674113
D3543773540834578
receptors553073540832559394074540833165104126163185212
in416774540831754
rat42377454083225577
central432974540833367105126148181196
nervous45427454083387394129166204230
system47887454083286087110144202
and500574540833472111
blood51337454083385492131171
cells.5319745408333668297123137
Neuropharmacology54737454083447911739407554083215897136168189248280312349365403443475
2006;443075540833469105140153
51:45987554083346574
923–932.468775540833467102139173206239251
60.39407653085367388
Godlewska404576540834482122137172223250280314
B,437576540833548
Olajossy‑Hilkesberger44397654083476395111149176202235257302318333363397424463498519557592614
L,506876540833246
Ciwoniuk513076540834055106144182198235265
M,541176540835568
Olajossy5495765408347639639407754083155380106139
M,409477540835568
Marmurowska‑Michalowska417777540835587108167205226263314341371404427483498530568601616654705732762795
H,498877540834457
Limon506077540833147105143181
J,525777540832436
Landowski530877540833265103142180231258288304