545
www.klinickafarmakologie.cz340804301076513320121425327329234035839843647950254457164568672477179183988990895196610061045
/26228043010757
Klin2698804301077091109157
Farmakol2874804301074178104179220258305324
Farm3217804301074178105179
2020;3414804301074487128171187
34(2):3619804301074489113156178193
78–833830804301074486133179221
/40718043010757
KLINICKÁ41488043010771114135194215268314372
FARMAKOLOGIE4540804301074292139211266312373415475534555598
A51588043010753
FARMACIE5231804301074291138211265317337380
8356558026012657114
PŘEHLEDOVÉ4549207012660124182256312369444520587645
ČLÁNKY5216207012660115187259327395
Aktuality414336501063873107149187218236268307
vo446636501063675
farmakoterapii455636501062968103158198234273303335371413447465482
astmy505436501063771104157194
bronchiale526336501063470111152187228246285316348
LITERATÚRA34458001234978134189250318368438498567
1.3437400853648
Global411741083446098138171186
Initiative61274108320587396111143165180213247
for875741083236183
Asthma.978741083416992130188221234
Global1232741083446098138171187
Strategy1434741083385980113135169208241
for1690741083236183
Asthma1793741083416992131188221
Management3438410835487125157196231289324362384
and7428410833472111
Prevention,869841083375892124159197218234272310323
2019.12078410833771102133144
Dostupné13688410834684111134172211250285
na:1671841083376982
www.ginasthma.org177084108351104158168207222343941083387096119158215248261299321359
2.34310400853652
The40910410833877112
European5361041083387495133172208240278
Lung82910410833673111150
White99910410835896111134168
Book.118210410834079117148163
Respiratory136010410834075102141156177210232269291325
health170010410834277109125147185
and190010410833775114
disease3431141083385379114146173208
in56611410831553
Europe.6341141083336990127167203215
ISBN8641141083154782128
978–1–84984–042–2100711410833467100137168201237274307342378415452489521556587
3.34312400853650
Národné4051241083447697133172210244
centrum66212410833064101122143181238
zdravotníckych9121241083286686119150187208246261292321355386423
informácií.13501241083124968105126183215247262276289
Zdravotnícka16511241083377595128159196217255269301330363
ročenka3431341083205789122159188221
Slovenskej5761341083324784116149187212241275290
republiky8801341083185290127166181196225258
2018.11501341083346798129142
ISBN13071341083124377122
978–80–89292–71–414411341083346699135170205242277311343377409443474505538574
4.34314400853651
Meilinger40714410835490105120135173212247268
M,68814410835468
Horváth76914410834482104139172193232
I,101614410831325
Laššán10541441083326592118151189
Š,125614410833344
et131414410833456
al.13831441083324760
Asthma14561441083416992130188220
control169014410833168106128149186202
and190514410833270109
perception3431541083397495126160199221237275313
from6721541083184077135
patient8231541083387193108143181203
perspective10411541083397495123162197230254269302336
in139215410831553
the14601541083226095
Central157015410834074112133155188203
European1789154108332699012716720234316410833270
region.4281641083245898113151189203
The64616410833675110
ASCERTAIN77516410834175115148184218255270315
survey.11051641083306788123157189199
Pneumo131916410833976111149207245
Update158316410834483122155176210
Europe18081641083367394131171206
Poster.3431741083357299122155177187
9–1054517410833572103134
June69517410832462100135
2017,84517410833468100129135
Vienna.9951741083365387125163196209
5.34318400853650
O’Byrne4071841083476097129151189224
P,64518410833540
Fabbri69918410833261101140162177
LM,89018410833187101
Pavord10041841083366799137158196
ID,12161841083135969
et129918410833456
al.13691841083324760
Asthma14431841083416992130188220
progression16771841083396098137158192219246261299337
and34319410833270109
mortality:46719410835795117141174190205227261274
the7571941083215994
role8661941083205773108
of98919410833756
inhaled10611941083145290122137172212
corticosteroids.12871941083326990115130162199226249283304341356395422435
Eur17371941083326990
Respir18421941083357097136152173
J343204108324
2019;38220410833569101131144
54:5412041083346981
1900491.63820410833464100136172205237247
6.34321400853651
Kuruvilla4062141083357192129162177192206238
ME,65621410835487100
Lee76821410833165100
FEH,88021410833264107120
Lee101221410833165100
GB.11242141083437992
Understanding122821410834380119153174201223256293331346383422
asthma16622141083325880118175207
phenotypes,18812141083387611134322410833877100134175211239252
endotypes61122410834078118157180214255291319
and94622410833776116
mechanisms108322410835894127166199238253280339366
of146422410834463
disease.15432241083446086122155182218230
Clin17892241083466177115
rev19202241083266194
Allergy3432341083415672106128166198
Immunol55623410831573131168206244260
2019;83223410833468100130143
56(2):9902341083346988121139151
219–233.11572341083346595133164199232245
7.34324400853643
OzdemirC,KucuksezerUC,AkdisM,etal.Theconceptsofasthmaendotypesandphenotypestoguidecurentandnoveltreatment39624410834775111144201214234283295339375405441470497530558590610664702714764793830843868932944987100810501063107511171155118812291264130113311363140114211447149415121554157816003432541083379312316720324027629632836640042546650253958762365669372974978181985287790994499110271040107711101151118612061238127412941335137114081455149115211554156815991618165134326410833252109143179199
strategies.555264108326486899120152190204237263275
Expert84226410833364102136156180
Rev103426410833569100
Respir11462641083366995132146166
Med132526410835488126
2018;14642641083346697126137
12(9):16142641083346278109126137
733–743.17632641083346799133164193224235
8.34327400853653
Papi41027410834174113129
A,55527410834661
Brightling6312741083416379118157179195210248288
C,93427410834659
Pedersen100927410834174115150172199235273
SE,12982741083387184
et139827410833962
al.14762741083375366
Asthma.15572741083477599138196229242
Lancet181527410833771110142176199
2018;34328410833468100131143
391:5022841083346799108
783–800.62528410833467101138174209245258
9.34329400853649
Holguin4042941083448197135172187225
F,64129410833238
Cardet6912941083407293130165187
JC,8932941083216174
Chung97929410834077114152190
KF,11822941083346873
et126829410833355
al.13362941083314659
Management140729410835486124155194228285320357378
of179829410833756
severe1866294108326619212621427410832054
asthma:2208741083325880118175206218
a243974108331
European2482741083336889126165199231268
Respiraory2762741083357096134149170202240261294
Society/American30697410833269102116150172205228265322356377392423456493
Thoracic35747410833271109130162194208240
Society21428410833271103119153176209
guideline.2367841083387590129164180195233268280
Eur2662841083336990
Respir2768841083357097136151173
J295684108324
2020;29958410833569101136148
55:3159841083346677
1900588.32528410833464100136170204240253
10.2142940085366984
Laššán2239941083316591117150188
Š,24399410833345
Téglás24969410833364103118150176
I,26889410831225
Laššánová2725941083326591117150188226258291
M.30299410835468
Targeting3110941083326081119154176191229267
asthma3390941083325881119177209
control36129410833168106127149186202
in214210410831553
real‑life22101041083225687103125141156176210
clinical24351041083334863101116148181196
practice26471041083396194126150165197231
by289410410833970
using29811041083376378116155
ICS/LABA31511041083165791116148192227268
combination.343510410833269127166182220252274289327365379
Klin21421141083355266104
Farmakol22621141083326183141173204241257
Farm25341141083336283142
2018;269111410833468100131143
33(3):28501141083346785118136147
21–27.30131141083346598130163169
11.21421240085366678
Muneswarao224012410835492130165192244277298331369
J,262512410832840
Hassali268412410834577103130163179194
MA,289712410835596111
Ibrahim30231241083195880113151166223
B,326212410833952
et332912410833861
al.34051241083365264
I3485124108319
tis35191241083264167
time36021241083254198134
to375112410832663
change214213410833169100138177211
the23681341083195792
way247213410835183113
we259813410835084
manage269513410835789127158197232
mild29391341083577287125
asthma:30771341083325881118176208220
an330913410833269
update339113410833776115147168202
in360813410831249
GINA367013410834359103144
2019.214214410833468100130141
Respir22991441083357097136151172
Res24871441083357097
2019;259914410833468100130143
20:27571441083356982
183.28541441083346599112
12.21421540085366883
Barnes22381541083356889128163190
PJ,24411541083355466
Szelfer25201541083326195110129164185
SJ,27181541083325769
Reddel280015410833570110149183199
HK,30121541083447994
et311915410833456
al.31881541083324760
Symptoms326115410833262121160182218277303
and357715410833270109
perception36991541083387495214216410833165104126142180218
of237416410833757
airway24451641083324768121154185
obstruction264416410833877104127149187219243258296335
in299416410831452
asthmatic30601641083325881120177210231247279
patients:33531641083397293109143181203231243
Clinical36101641083405670108123155188204
implications214217410831572110126141172205226241279317343
for25001741083155374
use25861741083376398
of269617410833756
reliever2767174108318526782116148182203
medications.298317410835791130145177209231246283321347360
J3358174108322
Allergy33931741083405570105126163195
Clin36001741083405570107
Immunol372217410831269214218410835795133171187
2019;234518410833468100130143
144:250318410833465102114
1180–1186.26321841083356293129167198225256292305
13.21421940085366883
Global22411941083446098137170186
Initiative2442194108316546991107139161176208243
for27001941083195779
Asthma.27951941083416992130188220234
Global30451941083446098138170186
Strategy32461941083345576109131165204236
for34981941083195778
Asthma35931941083416992130188220
Management214220410835487125157196231289324362384
and254120410833472111
Prevention,26692041083355690122157195216231269308321
2018.300520410833670102133146
Dostupné316920410834583110133171210249284
na:34702041083387082
www.ginasthma.org356920410835110415816820722221422141083387096119158215248261299321359
14.21422240085366883
Global22382241083435997136168183
Initiative2437224108312496486101133154169201235
for26872241083165374
Asthma.27742241083406891128186218231
Diificult‑to‑treat3017224108345607593109141178193215235257293316339360393425446
&3475224108339
Severe35252241083336799133154187
Asthma372522410834168214223410832260118150
in230723410831553
adolescent237523410833271109125160187219253291312
and270323410833270109
adult282723410833271109124146
aptients.29892341083317193108143181202230244
Diagnosis32482341083456193132170208235250276
and353923410833270109
management.366323410835890128214224410833270105162197235256269
V2.024242441083357082117
April255424410834079101116131
2019.26982441083346799129139
Dostupné285024410834583110133170209247282
na:31442441083387082
www.ginasthma.org3238244108350103156167205220258289316339376434466479516538576
15.21422540085366984
Papi224125410834173113129
A,238625410834660
Canonica246225410834679117156195210243276
GW,2759254108344103113
Maestrelli289325410835588123150174195230246261276
P,318525410834145
et324625410834062
al.33242541083375366
Rescue340525410834177104137175210
use363125410834369105
of375125410834363
beclomethasone214226410833975107123161220255277316348375413452487
and264526410833775114
albuterol27752641083375291130152186208245261
in305226410831958
a3125264108337
single31772641083324785124139174
inhaler33672641083205896129144179200
for35832641083236183
mild36872641083577288127
asthma.21422741083325881120177210223
N2380274108345
Engl244027410833371110125
J2580274108325
Med262027410835490129
2007;276427410833569105137147
356:292627410833568102114
2040–2052.305627410833468104140178210244278311324
16.21422840085367187
Calhoun22452841083457995133172211250
WJ,25162841083588092
Ameredes2624284108347106142163198238274301
BT,29412841083417584
King30412841083415896136
TS,31932841083387286
et329428410834063
al.33732841083375366
Comparison345528410834683143182216238254281320359
of214229410833857
Physician-,221529410834078109137152184199232270293305
Biomarker-,25362941083415695153186208239273295315327
and287829410833876116
Symptom-300929410833868128167190227286309
Based333329410834174101137177
Strategies35252941083386081115137171211226261289
for3941741083185678
Adjustment40347410834685100138164187246281319341
of43907410834362
Inhaled4467741083205897129144179219
Corticosteroid47017410834583104129144176213240263297319356372411
Therapy51277410833877112133167206237
in53807410831957
Adults5458741083417911713239418410832250
with4011841083516790128
Asthma.4155841083467497136194227240
The44118410833877112
BASALT45398410834182116157190219
Randomized47738410834174112152190249264294328368
Controlled51568410834683122143165203219234269309
Trial.5480841083385671104119132
JAMA39419410832464120162
2012;41189410833468100130142
308(10):42769410833468104123154186204216
987–997.45079410833570103135170205238244
17.39411040085366876
Martinez403310410835487108133148186221251
FD,42991041083337889
Chinchilli44031041083407893131163201216232247262
VM,468110410833590104
Morgan480110410835492114152184222
WJ,50391041083587991
et514610410833456
al.52181041083324760
Use529410410834470105
of541510410833756
beclomethasone548710410833974107394111410831553111146169207239266304342377
dipropionate43331141083385392114151190206244282315336370
as471711410833259
rescue47911141083205481113151186
treatment49921141083204276108130188223261282
for52901141083175576
children5381114108331698499138159193231
with39411241083506688126
mild40791241083577287126
persistent42181241083387394121136162185218256277
asthma45081241083315881118176208
(TREXA):47311241083165188121161203222234
a4978124108331
randomised,50241241083185189128165223238264299338350
double­538712410833876114152168203225
‑blind,3941134108321617792130169181
placebo‑controlled41381341083385486119152191230254287324363384406443459474509548
trial.4702134108321435890106119
Lancet483613410833165103135169191
2011;504213410833468100128136
377:519313410833567101111
650–657.532013410833468102140177211244250
18.39411440085377188
O’Byrne40501441083486299132155195231
PM,429714410834196110
FitzGerald44231441083385477108155192214248264304
M,474814410835569
Bateman48331441083427698133192226265
ED,51141441083388596
et522614410834063
al.53051441083385467
Inhaled53881441083216099132148184225
Budesonide‑Formoterol394115410833573112147174212251266305340363397434456514552574608629667683
as463915410833460
Needed471715410834479115154189229
in496115410831755
Mild50331541083557085124
Asthma.51751541083416892130188220233
N5426154108344
Engl548615410833472111126
J3941164108324
Mešd398016410835590117156
2018;415116410833468100131143
378:43101641083346699112
1865–1876.443716410833465100134171201232265297311
19.39411740085377186
Bateman404417410834580103139199233273
ED,433417410834390102
Reddel445317410834582124165201218
HK,468817410835592108
O’Byrne481217410835872111144168208245
PM,5074174108345101116
et520617410834568
al.52911741083425872
Inhaled538017410832564104138155192233
Budesonide‑Formoterol394118410833675115150178217257272312348372407445467527566588623645683700
versus46561841083387395123161188
Maintenance486518410835689105143166200239272311344379
Budesonide526018410834180120155183222262277317353
in394119410831553
Mild40091941083547085124
Asthma.41481941083416992130188220234
N4397194108345
Engl445719410833371110125
J4597194108324
Med463719410835489129
2018;478119410833468100131143
378:49401941083346699112
1877–1887.50671941083346598133165196227262295301
20.39412040085367287
Beasley404120410833571102129144179211
R,426520410833549
Holliday43272041083458399114129168200231
M,457120410835568
Reddel465220410833671110149184200
HK,48652041083448094
et497220410833457
al.50422041083324760
Controlled511520410834077116137159196212227262301
Trial5430204108332496597112
of555620410833756
Budesonide‑Formoterol394121410833573112147174212251266305340363397434456514552574608629667683
as463721410833259
Needed471021410834479115154189229
for49542141083175576
Mild50442141083547085124
Asthma.51822141083416992130188220233
N5429214108345
Engl548821410833270109125
J3941224108324
Med398022410835590130
2019;412522410833468100130143
380:428322410833469104117
2020–2030.441622410833468101135173204238272306319
21.39412340085356880
Hinds40332341083435895133158
D,420323410834555
Gibbons42702341083435896135172210235
DC,45172341083458597
Gunsoy462623410834381118143180211
NB,48492341083447991
et495223410833355
al.50192341083314658
Eligibility5089234108332466199113151166181195217249
for53532341083165273
newer543823410833771121154175
biologic39412441083395492108146185200232
therapies41892441083195792113146185201235262
in446624410831250
severe45292441083266193128149183
asthma,47252441083315881119177209222
re‑analysis49622441083195375108146178193225252267293
of526824410833756
the53392441083205893
IDEAL54472441083125891134166
study.39412541083264987126158168
Poster41252541083357298121155176
No.43172541083458395
1008442825410833465102137
(A5926).45802541083196096128162195213224
ATS482025410834170103
International49392541083145274108129168200222237275313346361
Concerence,53152541083407711614818220323727539412641083316577
Dallas,40332641083457893108140167180
May422826410835587118
17–22,43612641083356496128163175
2019.455126410833569100131142
22.39412740085357186
Chapman403927410833976107145202233270
KR,43212741083357184
Albers44172741083405593127148174
FC,46032741083327183
Chipps46982741083397690128167193
B,490327410833446
et496127410833455
al.50282741083314658
The509827410833270104
clinical5214274108331466097111142174189
benefit541527410833872109143160177198
of394128410833757
mepolizumab401328410835792131170186201230268326358398
replacing44262841083205594110142174189227266
omalizumab470728410833796128143158187226284316355
in507728410831553
uncontrolled514528410833775107144183204226263279294329368
severe55282841083266139412941083316586120
eosinophilic40732941083347299113151189228266281296310342
asthma.44272941083325881119176208221
Allergy46612941083405570105126163195
2019;48682941083346899129142
DOI:502229410834593109121
10.1111/all.13850.51562941083346577107135162189211241256271283314343377411444457