333
KLINICKÁ341804301074588109168189242288347
FARMAKOLOGIE708804301074392139212266313373416475534555599
A13288043010753
FARMACIE1402804301074292139211266317337381
/18048043010757
Klin1880804301077091109157
Farmakol2057804301074278105179220258305325
Farm2402804301074178104179
2020;2601804301074386128171187
34(4):2807804301074489113155176191
171–1743017804301074481122163202239277
/33148043010756
www.klinickafarmakologie.cz4568804301076513320121425327329234035839843647950254457164568672477179183988990895196610061045
1741368026012657109161
HLAVNÍ341207012670127198263336370
TÉMA732207012658115205275
Izotretinoín3413650106154887117153185219237278318336377
v733365010637
liečbe7853650106304879114150183
acne98236501063972114146
vulgaris114236501063879110147187223241273
–1430365010646
úloha149136501063970109151191
alternatívnych16973650106386998130166208248276293332373410443484
dávkovacích219636501063877111147186223260293311345386
režimov259736501063467101119172213250
ating343554083325469107146
acne.5045540833264102137149
Clin669554083405570108
Dermatol7925540834581102160193214251267
2004;10755540833468104140152
22:1242554083346982
439–444.13395540833467100138174211248261
17.343653085366876
Agarwal4346540834179112133186219234
U,6846540834354
Bhola7536540833574112128160
K,9286540833550
Besarwal993654083357097130151205237253
R.12616540833550
Oral13266540834768101117
isotretinoin1458654083144079101122156178194232270285323
in17976540831452
diffe‑186465408338537392126149
rent343754083215593115
dose4737540834482109144
regimens6327540832660100115173208247273
for921754083236183
acne10197540833769108143
vulgaris:1177754083377691130163184200226238
A143175408346
randomized1493754083255897136174233248277311351
com‑18597540833774132155
parative343854083397293126148163195230
trial.58885408320425789105118
Indian721854083145291106138176
J91285408323
Derm9508540834580101160
Venereol11258540833467105140161196234250
Leprol13908540833165104126163179
2011;1584854083336799127135
77(6):1734854083336884117135147
688.18978540833368103117
18.343953085356884
Nevoralová,4399540834479110147168200215253284316329
Zuzana.783954083357099132169201214
2012.1012954083316495125137
Izotretinoin116495408312407798119152174189226264279316
v149595408328
praxi.1538954083365789120135148
Praha1701954083325284122153
:186995408310
Mla‑1894954083516698120
dá34310540833870
fronta,4291054083184077116137170183
a.62710540833246
s.,6881054083264052
2012.75610540833468100130142
9691310540833570
s.99810540832337
ISBN10501054083154782128
978-80-204-2695-6.119310540833467100123159194218249283319342373407441475497534548
19.3431153085366780
Tan4331154083325996
J,54311540832132
Knezevic58911540833270103132165196210241
S,84411540832941
Boyal8991154083326999131146
S,105911540832941
Waterman111411540835484104137157214245282
B,141011540833244
Janik14681154083215288102131
T.161411540832937
Evaluation16651154083296092106142173194208245282
of196111540833452
Evidence3431254083326277114148184215247
for6041254083155171
Acne68912540833767104137
RemissionWith84012540833265121135160185199235272339354375412
Oral12661254083436395109
Isotretinoin1389125408311367393113146167181217254268305
Cumulative170812540833671127163177207228242273306
Dosing34313540834582108122158196
of55313540833452
120–150mg/kg.6191354083316093129159188221288326351381417429
J1063135408320
CutanMed10981354083367193124161226260298
Surg14111354083286585121
2015;15471354083306394123132
20(1):16941354083306382112126136
13–20.18451354083305994125157169
20.3431453085367186
Borghi4411454083357394132169184
A,64014540833852
Mantovani70714540835284121142179210243280295
L,101714540832942
Minghetti107414540835167104142180214236260275
S.136414540833043
et142214540833153
al.14901454083294457
Low‑cumulative156214540832865116138171208265302317349371385418451
dose34315540833875101135
isotretinoin493155408312377496117150171186223261276313
treatment8201554083194073104125182217254275
in111015540831148
mild‑to‑moderate11731554083546983121143165201224281319358392412444466499
acne:16861554083296098132144
effica‑1845155408331486683115147169
cy34316540833165
in42316540831452
achieving49016540833163101116151183199237276
stable7811654083254881120136171
remission.96716540832054112127153180195233271284
J1267165408323
Eur13051654083326889
Acad141016540834071104143
Dermatol156816540834580101160192214251267
Vene‑185016540833567106140164
reol2141554083215593109
2010;22665540833468100131144
25(9):2425554083356987120138149
1094–1098.25905540833465101136174205236271306320
21.2141653085366981
Boyraz22406540833674104125158186
N,24416540834961
Mustak25166540835996122144176206
PK.2736654083407488
Comparison28386540834581139177210230245270307345
of31986540834160
the3272654083266398
efficacies338465408338567492123156187201235261
of36606540834160
in‑3734654083195678
termittent2141754083225474131145166189221258278
and24337540833572109
continuous25567540833571108128142178214251288313
low‑dose28837540831855105125164201226260
isotretinoin3157754083184380100120153174188224261275312
regimens3483754083245795109165198235260
in37577540831855
the2141854083225892
treatment2247854083234376106126183217253274
of25358540833856
moderate26058540835996134167187219239271
acne28908540833364101134
vulgaris.3038854083337084122153173187211224
Int3276854083165272
J336285408326
Dermatol34028540834680100157188209244259
2013;3675854083356898127137
52(10):2141954083346682112142159170
1265–1267.2325954083326193125160190218251282287
22.21411053085367287
Kaymak22411054083356898156188218
Y,247410540833341
İlter2530105408312274982103
N.264810540834255
The271910540832968103
effectiveness28371054083315069103136159174207240278313339365
of321810540833453
intermittent32861054083125071104125183198220244277315336
isotre‑3637105408313387698119153175
tinoin21411154083223775113129166
treatment23231154083234579111133191226264285
in262411540831654
mild26941154083597489128
or283811540833960
moderate291411540835997137172193226248282
acne.321111540833466104139151
J3378115408326
Eur34191154083357192
Acad352711540834374107146
Der‑368811540834883104124
matol214112540835790111148164
Venereol232112540833568106141162196235251
2006;258712540833569105140153
20(10):27551254083346888120151169181
1256–1260.29521254083346499133171202232265301313
23.21411353085367287
Lee,224213540833166101113
J.237013540832335
W.,24211354083566679
Yoo,251513540833468107119
K.264913540833349
H.,27131354083435669
Park,27971354083346687118132
et294413540833355
al.30151354083304558
Effectiveness30891354083315069103136160175208242280315342369
of347313540833655
conventi‑354413540832966105136170209230245267
onal,214114540833776108123136
low‑dose229214540831755106128169207234269
and257614540833472111
intermittent27021454083175576110131190205227251285323345
oral30621454083396194109
isotretinoin31871454083164281103124158180196234272287325
in352714540831755
the35971454083246297
tre‑37091454083244579103
atment214115540833254112147185206
of236315540833757
acne:243515540833264103138150
a2600155408333
randomized,26481554083215492131169228243272306345358
controlled302215540833168107128150187203218253292
comparative332915540833269127167200221254275291323358
stu‑37021554083265088110
dy.21411654083387080
Br223616540833657
J2308165408325
Dermatol234816540834581102160193214251267
2011;263116540833468100127135
164(6):278216540833465102121154172184
1369–1375.29821654083346498132170200230262295307
24.3939553085367186
Akman40395540834171130163201
A,42555540834054
Durusoy43245540834482103142168206237
C,45775540833851
Senturk46435540833166105126164185216
M,48745540835367
et49565540833255
al.5026554083304659
Treatment5100554083314882114136194229267289
of54045540833655
acne54745540833163101136
with3939654083516689127
intermittent4081654083145274107129187202225249283321342
and44396540833169108
conventional45636540833067106137171209231246284323355370
isotretinoin:4949654083144078100122156178193231269285323335
a529965408332
randomi‑5346654083205391130168227242264
zed,39397540832862102115
controlled40697540833470109130152189205220255295
multicenter43797540836097113135150182216254276309331
study.4725754083295290129161171
Arch4911754083436596134
Dermatol50607540834883105163195217254270
Res53457540833873100
2007;54607540833771107140150
299(10):39398540833468104123154186204216
467–473.41708540833571104136173205239252
25.3939953085377489
Goulden40509540834484123139179215254
V,43209540834251
Clark4387954083466295117148
S.45519540833852
M,46199540836175
Mcgeown47109540836194132168208260300
C,50269540834659
Cunliffe51019540834684123139154175194229
W.53469540836474
J.54369540833043
Tre‑5495954083395691115
atment393910540833254112147185206
of416110540833655
acne423210540833163101136
with43831054083506688126
intermittent45251054083145173107128186202224248282320342
isotretinoin.48821054083144078100122156178193231269285323336
Br523310540833556
J5305105408323
Dermatol534310540834580101160192214251267
2008;393911540833468104140152
137(1):41061154083356497113145159171
106–108.429211540833466102139170202237251
26.39391253085356983
Akman,403112540834069125155191202
A,424612540833749
Durusoy43091254083407695132156192221
C,454312540833647
Senturk46031254083286197117152172200
D.481612540834150
et488012540832950
al.49431254083274152
Treatment50081254083294476106125181214250269
of529112540833250
acnewith53541254083275893126186199220256
intermittent39391354083155171103122179192213236268304324
and427713540832864101
conventional43921354083276399129162198218232268305335349
isotretinoin:4755135408310357192112144165178214251265301312
a5080135408328
randomized,51221354083174884122158214228255288326337
cont‑547213540832863100120138
rolled3939145408321567185118156
multicenter410914540835692106127141172204241261293313
study.44361454083254683121151160
Arch46101454083395989125
Dermatol47491454083447898155186206242256
Res;50191454083346893104
299(10):51371454083336599117147177194205
467–473.53561454083336799130165196229240
27.39391553085367181
Amichai403615540834199115148187220236
B.428915540833448
Long‑Term435315540833068108147171201233255314
Mini‑Doses468415540835269108124147195234262298325
of502615540833556
Isotretinoin50981554083144180103125160183199238277294332
in544715540831352
the55151554083205995
Treatment39391654083335187120143203239279301
of425716540833960
Relapsing43331654083377390124165193209248289
Acne.463816540834376115151165
J4820165408325
Dermatol486216540834784106166200223261279
2003;515716540833671109143156
30:53301654083367186
572.543316540833570106120