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Farmakol2916804001074279105179220258305325
Farm.3261804001074178105179195
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KLINICKÁ4170804001074588109168189242288346
FARMAKOLOGIE4538804001074291138210265312372415474533554598
A51578040010753
FARMACIE5231804001074292139211266317337381
8356558020012657114
HLAVNÍ4945200012671127198263336370
TÉMA5337200012657114204274
Bezpečnost400536001063466101135167202243284317349
biologické43703600106345292124163203220255290323
a4709360010637
cílené47623600106335081114155187
léčby49653600106296196132168
v5149360010636
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24.343620085367186
Molloy4426200835493109124162193
ES,648620083336779
Calabrese740620083407389121160182216242277
LH.1030620083327790
Progressive1133620083355693133154188215241256289323
multifocal14696200835795110132148167205237270286
leukoencephalopathy17686200831449871171551902283437200833165104143175190228268301323361392
associated750720083325885123156171203225259298
with1064720083506688127
immunosuppressive12067200831573130168206244271308347387408443469496511543578
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in3438200831552
rheumatic408820083205893130187219241256287
diseases:708820083385378113144170205232244
evolving9648200833466103119151166204242
role1219820083205773107
of13398200833756
biologic1407820083395492107145184199230
therapies.1650820083215994115147186201236262275
Arthritis1938820083416234392008322608197119134160
Rheum.5199200833573108146204217
2012;64(9):3043-3051.7529200833468100130142178214234266284296331366402435456489523557589598
25.3431020085357184
Eshwar4391020083325995144176196
V,64710200833543
Kamath70210200833466123154175212
A.92610200834054
Assessment9911020083416793127153178234268305326
of132910200833655
safety13951020083265876109131163
profile15701020083385995112128143176
of175810200833755
secukinumab1825102008326599112815717234311200833875133165204
in56411200831553
real-world6331120083215587102124176214235251290
scenario9401120083265892130162183199237
using11931120083376479116155
United13651120083448297119153192
States15741120083325386108142169
food17591120083185695134
and191011200833270109
drug3431220083385998137
administration50012200833271129144182197223247268301323338376415
adverse93512200833271104138159187222
event117712200833466101139160
reporting13581220083205594133154179194232271
system16501220083265986109143201
database.187112200833870921253431320083397298133145
Sci5041320083326480
Rep.59913200833570109122
2024;14(1):1222.73613200833469101133145175206226257272284314343378413425
26.3431420085357085
Davidson44014200834576107122159185222260
L,71214200833144
van76814200833163100
den88014200833771108
Reek100014200833569104133
JMPA,114514200832478112149162
Bruno13191420083355693130167
M,149814200835467
et157714200833355
al.16441420083314658
Risk17141420083355075104
of183014200833755
candidiasis1897142008331631003431520083385291106137163178203
associated5591520083315783121153168199221254293
with8641520083506688125
interleukin-1710021520083145273106127142176214243259296318349378
inhibitors:13921520083155289104143158180216237264276
A1681152008340
real-world17341520083205485100122173210231247285
observational34316200833777104139160194227249264302341373389
study7501620083264987126158
of92616200833756
multiple100016200835795110133148187203238
independent12561620083145291126165201239278313351373
sources.164716200832664102123154188215228
Lancet1893162008332651033431720083316587
Reg44617200833570109
Health57117200834479111126148187
Eur.7731720083336990101
2021;13:100266.88917200833468101133141171201212242273310342376412425
27.3431820085367180
Alsakarneh4391820083415682116146179200239274312
S,76818200833345
Al83018200834157
Ta’ani9041820083326072102140155
O,107618200834758
Aburumman115118200834180119140178236294326364
R,153218200833549
et159818200833456
al.16711820083324760
Risk17481820083365177107
of187218200833757
de194518200833873
novo34319200833876108145
inflammatory504192008315537087119177235267289326348382
bowel90219200833877128163178
disease10961920083395480115147173208
in132019200831553
patients13891920083387193108143181203230
with16361920083506688126
psoriasis177819200833966104126141173200215241
and34320200833270109
psoriatic46820200833965104125141173195210242
arthritis7262020083325378116137153175190216
treated9592020083214377109130164204
with11792020083506688127
IL-17A1322202008314466192122158
inhibitors:14962020083155391106145160183220241269281
a1793202008332
population-based184120200833978117155343212008315476984122161183223256282317357
Study.7142120083325391130162172
Aliment9002120083415772129164202224
Pharmacol113821200833572105126184217249286302
Ther145421200833271106128
2025159521200833569102136
Apr174521200834181102
7.186121200833440
doi:19152120083387692104
10.1111/apt.70139.3432220083346678109137164192214244283305319353386418448481492
Epub85022200833372110149
ahead101422200833270105137176
of120622200833756
print.12772220083396176114136149
28.3432320085367187
Lebwohl44423200833165103154191229243
MG,70223200835498110
Papp82723200833566104143
KA,9852320083347891
Marangell109123200835486107139176214249264278
LB,13832320083326779
et147623200833456
al.15462320083324659
Psychiatric16192320083356192123160175206227248263294
adverse1927232008332713432420083326586112147
events5072420083346699136157184
during7092420083387595110147186
treatment9122420083224276107128185220257278
with12072420083516688125
brodalumab:13492420083396097135167182219276307346357
Analysis172424200834178110125156182196222
of196324200833756
psoriasis34325200833864101121136167192206231
clinical585252008331455995109140172186
trials.782252008321425687101126139
J932252008324
Am96725200834097
Acad107525200834071102140
Dermatol.12262520083457999156187208244258270
2018;78(1):81-89.e5.15072520083346797127138170202220251264275308339357391424434468501512
29.3432620085357083
Wu43726200835692
S,54126200833143
Xu59626200833872
Y,68026200833542
Yang73426200833563100137
L,88326200833144
Guo93926200834379116
L,106726200833144
Jiang11232620083233868105143
X.127826200833750
Short-term134026200833269106126150169190223243300
risk1652262008320356089
and175326200833168105
longterm187026200831552891273432720083225577135
incidence4972720083155385100139174212244278
rate7942720083205375109
of92227200833757
infection9982720083145271105138162178216254
and127127200833270109
malignancy139927200835790105120159197229267299333
with17512720083516689127
IL-171897272008315476292122
and21386200833270109
IL-23226262008315476293128
inhibitors2405620083155391106145160183220241269
in26896200831552
adult27576200833271108124146
patients2918620083397294109144182203231
with3164620083516789127
psoriasis33076200833865103125141173199214240
and35626200833270109
psoriatic36876200833865103213872008321366890105137
arthritis:2294720083315377115136152175190216228
a254172008331
systematic2591720083265885109142200233254270302
review2911720083215587103137189
and31187200833270109
meta-analysis.32457200835792115147170202240273288320347362388401
Front3665720083325289127149
Immunol.21388200831573130168206244260273
2023;14:1294416.24268200833569102136148178209221251281315351388418449462
30.2138920085377692
Huang22619200834585120160201
PF,2493920083367178
Huang26029200834585119160201
TY,2834920083337584
Cheng29499200834181118159200
YC,3180920083367791
et33029200833559
al.3392920083335064
Clinical3487920083415874114131165200217
insights3735920083155521381020083274383123145174
into23341020083155577116
IL-232472102008315486497133
inhibition:26271020083155494110151167191207247287300
risankizumab2949102008321376599139170188218258318352393
for33641020083195880
Crohn’s346610200834164102143182195221
disease3709102008339558321381120083356896133
through22961120083226284123163204244
a2564112008333
systematic26221120083266189114149209243266283316
review29631120083215791108144198
and318511200833373113
meta-analysis332311200835996119154178211251285302335364380407
of375511200833858
randomized21381220083215695136176237253283319360
controlled252012200833371111134157195212228265306
trials.2848122008323456295112139154
Therap302412200833474111133168209
Adv325512200834282117
Gastroenterol.339412200834579107131154193230270292328350389406420
2025;18:17562848251338743.213813200833468101136147177208220250279312346380413450486519554585615648683716746779791
31.21381420085367083
Long224314200833270109149
M,241314200835670
Danese250414200834679117153181217
S,274214200833346
Ott28091420083487297
E,292714200833346
et299514200833457
al.30731420083324862
Safety31561420083336686121144178
of335614200833757
ustekinumab34341420083386589123154171210248307340380
across21381520083326485122149176
approved232915200833271111133170202236276
adult262015200833271109124146
indications:27821520083155392107139172194209247285312324
pooled312215200833877116132167206
safety33441520083265978113135169
analysis352815200833270103118150177192218
in376115200831553
Crohn’s21381620083406198137175187212
disease,23661620083385380115146173208220
ulcerative26021620083385385119140173195210242277
colitis,2895162008331688499122137163176
psoriasis,308816200833865103125140172199214240253
and335816200833169108
psoriatic348316200833965104125141173194210242
arthritis3741162008332532138172008322608197119134160
through23181720083226081118156195233
up257117200833776
to266717200832158
52745172008334
years.27981720083316597119146159
Abstract.297717200834180107130152185217241254
Am325117200834199
J3369172008324
Gastroenterol.341317200834476103126147185220258280314335372388401
2021;116():p213818200833468101133141171199230249270282321
S441.247518200833268105136145
32.21381920085367187
Liu22451920083314784
R,235019200833549
Li241919200833247
Z,248719200833751
Ye255819200833566
L,264519200833145
et271019200833456
al.27871920083324760
Risk28671920083365177107
of299519200833756
tuberculosis30721920083215999134155187224240278305320346
and343819200833270109
hepatitis356719200833873112145167182205220246
B2138202008336
reactivation21952020083215689122147163196230253268307347
in256320200831554
patients26382020083397396112147186209237
with28962020083526891130
Crohn’s304820200834062100140179191217
disease32862020083395582117150178213
on352120200833877
ustekinumab:36192020083386589124155172213821200833875133165204217
a2374212008332
nationwide24252120083387092107145184234250288323
real-world27682120083205486102124176213235251290
study.30772120083264987126158168
Inflamm3265212008314527087119177235
Bowel351921200833574125159175
Dis.37132120083456187101
2024;30(1):45-52.213822200833468101133145180214234266280292326359381415448461
33.21382320085356983
Honap223323200834380117149186
S,243123200833244
Irving2486232008315356883120158
PM,26552320083348799
Samaan276623200833263119151182218
MA.299623200835394108
Ustekinumab-induced31152320083436890122152167204240296327365388403440477514545577615
inflammatory37422320083145121382420083173466123181213234271292326
demyelinating247724200833872130160194210225262294316331368407
polyneuropathy28972420083387793124163197235256293332365386424455
in336524200831452
a3429242008332
patient34742420083387193108142180201
with36882420083506688126
ulcerative21382520083375385118139172194209242276
colitis.2430252008331688499121136162176
J2621252008325
Crohns26612520083406198137175201
Colitis28772520083407793108130146172
2023;17(1):144-145.306425200833468101136147178207223255269281311342379402433464497509
34.21382620085367388
Merrill224426200835490111133148163178
JT,24402620083245867
Ginzler25242620083446097127143177199
EM,274026200833388101
Wallace285826200835889105120152184218
DJ,30932620083456880
et319026200833456
al.32632620083324861
LBSL02/9933412620083316799130164197224258293
Study36522620083325391130162
Group.213827200834365102139178190
Long-term234127200833168106145167189223244302
safety26552720083265978112134167
profile28352720083386096114131146180
of302827200833756
belimumab30972720083387389103160198255287326
plus34362720083385491117
standard35662720083254881118157189210248
therapy3934620083226095116149188219
in41716200831452
patients4241620083387193108143181203230
with4488620083516789127
systemic4633620083265885108142200215247
lupus4897620083155392130156
erythematosus.5071620083345589114152187245277299336362400426440
Arthritis55286200834162393472008322608197119134160
Rheum.41107200833573108146204217
2012;64(10):3364-3373.43437200833468100130142178214234265297315327362395430466489522555587621633
35.3934820085367288
Xie4039820083385591
W,41478200835768
Huang42328200834483117156197
H,44458200834559
Zhan45218200833777110150
S,46878200833347
et47518200833458
al.4825820083324963
Risk4905820083355280111
of50338200833758
psychiatric51088200833866100133173189222246268285319
disorders544482008338548212114439349200833977101131
and40899200833374116
all-cause422992008333516893129165205234272
mortality452692008359100124151187205222247283
with4834920083527095136
belimumab4994920083407996114175216277312354
therapy53739200832263101125160203237
in393410200831556
patients401410200834076100117155196220250
with42881020083527095136
systemic44481020083276292118154215233267
lupus47401020083155597139167
erythematosus:49321020083355895122163201262297322361391431459474
a5431102008332
meta-analysis54881020083599639341120083215579112151184201233262277305
of425411200833757
randomised43271120083205493133172231247274310351
controlled469311200833169108131154192209225261301
trials.5010112008321446093110137151
Lupus517711200833169109148175
Sci53681120083326581
Med.546511200835490130145
2021;8(1):e000534.393412200833470104137146183203237252266302339376414449484520534
36.39341320085367288
Kim403913200833551109
SS,41651320083326477
Kirou42591320083355172109148
KA,44231320083357993
Erkan45331320083335484118156
D.470513200834657
Belimumab47791320083357086101158196254286325
in512113200831553
systemic51901320083265986109143201216248
lupus54541320083155392130156
erythematosus:39341420083345590115153188246279301338365402429441
an439614200833270
update448714200833776116149171205
for47121420083195778
clinicians.48111420083314762100115147162195233259273
Ther510514200833272107128
Adv525414200834180112
Chronic53871420083407899137176191223
Dis.39341520083456187101
2012;3(1):11-23.405015200833468100130142177195227241253283311329360395408
37.39341620085367079
Tummala402816200833366124182214229262
R,430416200833650
Abreu436916200834180102136173
G,455716200834457
Pineda46291620083355088123162195
L,483816200833245
et489816200833457
al.49691620083324860
Safety50441620083336685119141175
profile52341620083396097115132147182
of543116200833756
anifrolumab550216200833270853934172008318407894131189221261
in421217200831553
patients42821720083397294109144182203231
with45311720083506688127
active46751720083326488104136171
SLE:48631720083336497110
an499117200833270
integrated50781720083155374108148169202224257297
analysis539317200833169102117149176191217
of393418200833757
phase400618200833977109136171
II419218200831530
and423818200833169108
III43621820083153045
trials.4422182008322435991106132146
Lupus458318200833269108146172
Sci47711820083326480
Med.486618200835489129142
2021;8(1):e000464.502318200833569102133141176196227242254288324360396432468505517
38.39341920085367288
McHugh404219200835487131169208246
J.430819200832436
Long-term436419200833169107146168191225246304
anifrolumab46881920083327085104126164180217275307346
safe50541920083265978113
in518719200831452
SLE.52591920083326397110
Nat53881920083457899
Rev550719200833570103
Rheumatol.393420200833574109146204237258295311324
2023;19(2):64.427420200833468101135147177207226260278290325362374
39.39342120085367184
Alves40312120083415688123149
C,419321200834053
Penedones425821200833569107141181219257292318
A,458921200834155
Mendes465721200835489127166200227
D,489721200834556
Marques496621200835486107145182217244
FB.52232120083326780
The531621200833271106
Risk54352120083355076106
of555421200833756
Infections39342220083155372106139163178216255281
associated42352220083325985123156171203225259298
with45542220083506688126
JAK47012220083246499
inhibitors48202220083155391106145161183220242269
in510922200831553
rheumatoid51822220083215994132190222244281296335
arthritis:5537222008332533934232008322608196119134160173
a4120232008331
systematic41642320083265986109143200233254270302
review44792320083205486102137188
and468023200833270108
network48012320083387395148186207238
meta-analysis.505223200835792114147169202240272287319346361387400
J5465232008324
Clin55022320083405570108
Rheumatol.393424200833574109146204237258295311324
2022;28(2):e407-e414.427424200833468101135148183216235269287299334370406439457493530560591604
40.39342520085357286
Szekanecz40332520083326093122155192226258287
Z,433225200833750
Buch439425200833572103140
MH,454625200835397109
Charles-Schoeman466725200833976108128143177203223254285322360394451482519
C,519825200833952
et526225200833355
al.53292520083314658
Efficacy5399252008332496784115147179211
and393426200833169107
safety40532620083265877110132165
of423026200833756
JAK42982620083246398
inhibitors44082620083145189103142157178215236262
in468226200831552
rheumatoid47462620083215893130186218239275290328
arthritis:50872620083315176113133149170185211223
update532226200833775114145167200
for55342620083185576
the39342720083215892
practising40382720083385991122145160185199236274
clinician.4324272008330455996110141155186223236
Nat45722720083447596
Rev468027200833468100
Rheumatol.479127200833572106143199231251287302315
2024;20(2):101-115.51182720083336698129140174207226259276287316346377395425451480492
Připravujeme5715080037217428736854866282097311491234139216521811
do244950900356163322
Klinické57154300347172249323485558682832974
farmakologie16025430034795240344582728877103211081267143015041649
a330854300347148
farmacie351254300347962413445827288519271072
HLAVNÍ5996000012367117183239307334
TÉMA9546000012352104187251
–12266000012350
Betablokátory12976000012357110145197256282338390441476532568621
v19396000012350
kardiologii20106000012351103138197222279305362420446471
PŮVODNÍ5996200012356122182251320388415
PRÁCE10356200012356112177234284
„599636008960
Retrospektívna739634001195199130159211248302351393427448493547592
analýza1353634001194598143163207250297
krvácavých1671634001194374122168212258302349393446
príhod2139634001195584105160214269
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extrémnych2497634001194992126155203284337379423476
INR2995634001192184134
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populácii32186340011955109165218238283328348368
zosnulých3608634001194092129181234254298342395
pacientov40256340011955101145165214267296347392
PŘEHLEDOVÉ5996540012356112164232282333402473532584
ČLÁNKY12046540012358107173240299360
„599670008960
Léčba739667001194592137192238
polymorbidních9986670011956110131175258311341396417471524544588641
pacientů16616670011955101146166214267296349
s20326670011937
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sklerózou2645667001193879102150179231270321375
„599683008960
Současná7396800011946100153197243279332377
farmakoterapie1138680001192672101183228270322352399428473528549597
neuropatické17576800011954102155184235291336366387431473520
bolesti22996800011955109131179216248268
„599696008960
Léčiva739693001194592137157203248
ze1009693001194188
skupiny1119693001193778132186207260302
ARTA14436930011958108156207
a16726930011945
jejich173969300119217090110155207
lékové1968693001192270112164208256
interakce2246693001192173103150179224266309356
se2624693001193786
zaměřením2732693001194087168217245292345365446
na3200693001195398
antikoagulancia3320693001194699128148190242288342395415460513557577622
KAZUISTIKA5997150012358125184249276328381408467534
„599732008960
Farmakokinetické739730001194687116198243284336379401454502533553598639687
interakce1448730001192073103149178224266309356
klozapinu1826730001194265118156203258278331383
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olanzapinu:2299730001195374119172212259314334387439456
kazuistiky2776730001194389130184204240272292334381
lékových3179730001192169111163208255299352
změn35537300011940122171224
při3799730001195584105
inhibici3926730001192173126147201222266286
CYP1A242347300011957109160205256306
…a59975400121100149
spoustu766754001213889142194231262314
dalších10987540012153104127163185227280
zajímavých1396754001214293116139219271317364405458
témat…1872754001213276157209240337
2025349705080022693185274369498351100754344
▼506959500253143
VYCHÁZÍ48966160015566142216301381458489
V51076330015566
ŘÍJNU4981650001556698148235320