Klin Farmakol Farm. 2005;19(1):47-48

ICHTHAMMOL AND TARS IN current DERMATOLOGICAL TREATMENT

doc. MUDr. Dagmar Ditrichová CSc
Klinika chorob kožních a pohlavních LF UP a FN Olomouc

The article deals with the importance of tar preparations in current dermatological practice. Because of their adverse effects (carcinogenic, phototoxic, nephrotoxic) and in accordance with EU legislation a highty limited use of coal tars in external treatment is recommended. In indicated cases (some forms of psoriasis) application of up to 5 % concentration of coal tar and up to 20 % of skin surface is possible with careful laboratory monitoring. In other indications bituminous tars (ichthammol, leukichtol) are adequate substitutes.

Keywords: Key words: external treatment, coal tars, bituminous tars, ichthammol, leukichtol.

Published: January 1, 2006  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Ditrichová D. ICHTHAMMOL AND TARS IN current DERMATOLOGICAL TREATMENT. Klin Farmakol Farm. 2005;19(1):47-48.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Goeckerman WH. The treatment of psoriasis. Northwest Med 1925; 24: 229-231.
    2. Fadrhoncová A. Farmakoterapie kožních onemocnění. Praha: Grada Publishing, 1999: 416.
    3. Griffiths WAD, Wilkinson JD. Topical therapy. In: Champion RH, Burton JL, Ebling FJG, eds. Textbook of dermatology. 5th ed. Oxford:Blackwell Scientific Publications, 1994: 3037-3084.
    4. Braun-Falco O, Plewig G, Wolff HH, Burgdorf WHC. eds. Dermatology. 2nd ed. Berlin, Heidelberg: Springer-Verlag, 2000: 1853. Go to original source...
    5. Thami GP, Sarkar R. Coal tar: past, present and future. Clin Exp Dermatol 2002; 27: 99-103. Go to original source... Go to PubMed...
    6. Rietschel RL, Fowler JF Jr, eds. Fisher´s contact dermatitis. 4th ed. Philadelphia: Lippincott Williams and Wilkins, 1995: 1117.
    7. Lim HW, Soter NA, eds. Clinical photomedicine. New York: Marcel Dekker, Inc., 1995: 415.
    8. Borská L, Fiala Z, Smejkalová J, et al. Possible genotoxic risk of combined exposure to pharmaceutical coal tar and UV-B radiation. Cent Eur J Public Health 2004; 12: S14-15.
    9. Harber LC, Armstrong RB, Leach EE et al. Preliminary report: modified Goeckerman therapy for hospitalized patients. J Invest Dermatol 1981; 77: 162-166. Go to original source... Go to PubMed...
    10. Diette KM, Gange RW, Stern RS et al. Coal tar phototoxicity: characteristics of the smarting reaction. J Invest Dermatol 1985; 84: 268-271. Go to original source... Go to PubMed...
    11. Stoughton RB, Dequoy P, Walters JF. Crude coal tar plus near ultraviolet light suppresses DNA synthesis in epidermis. Arch Dermatol 1978; 114: 43-45. Go to original source... Go to PubMed...
    12. Lavker RM, Grove GL, Kligman AM. The atrophogenic effect of crude coal tar on human epidermis. Br J Dermatol 1981; 105: 77-82. Go to original source... Go to PubMed...
    13. Zelenková H, Linkeschová E, Stracenská J. Ichtyol a jeho renesancia v novom tisícročí. Derma 2004; 4: 4-6.
    14. Warnecke J, Wendt A. Anti-inflammatory action of pale sulfonated shale oil (ichtyol pale) in UVB erythema test. Inflamm Res 1998; 47: 75-78. Go to original source... Go to PubMed...

    Return to the content


    Clinical Pharmacology and Pharmacy

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.