Klin Farmakol Farm. 2005;19(2):95-99

Pharmacotherapy of malaria in Czech Republic

doc. MUDr. Jiří Vaništa CSc

I. infekční klinika 2. LF a Katedra infekčních nemocí IPVZ, Praha

Malaria is a serious problem of healthcare systems worldwide. Annually, it affects 300 million people and causes 2 million deaths. In non-malaria countries, more than 30,000 people get ill annually by contracting the disease in tropical and subtropical areas. The mortality of such imported malaria fluctuates around 1 %, but in a serious course of the disease it may reach as much as 20 %. A life-threatening course of malaria is prevented by early diagnosis and early initiation of effective chemotherapy. For this reason, suspected tropical malaria is an acute situation in infectious medicine, which requires diagnostic and therapeutic efforts to be done as soon as possible. The disease can be prevented by protection from an infected mosquito and by chemoprophylaxis. Antimalarics available in Czech Republic include chloroquine, proguanil, mefloquine, primaquine, doxycycline, quinine and a combination of atovaquone and proguanil. The article presents an overview of their use for treatment and prophylaxis of malaria.

Keywords: Key words: imported malaria, antimalarics, treatment and chemoprophylaxis.

Published: January 1, 2006  Show citation