Klin Farmakol Farm. 2005;19(3):146-148

Primary compliance with lipid lowering therapy

Jan Strojil, Karel Urbánek, Mgr. Lucie Sobolová

Ústav farmakologie LF UP a FN Olomouc

Compliance with medication therapy is a well-recognised and important issue. This paper gives a short overview of published work on compliance in lipid-lowering therapy, with special focus on primary non-compliance in statin therapy. We analysed prescription database in the Teaching Hospital in Olomouc and identified all prescriptions issued for lipid-lowering agents in 2003. These data were compared to the database of claimed prescriptions obtained from the insurance company. There were 12,182 packages prescribed to 2,715 patients. 8.1% of prescribed drugs remained unclaimed by 17.2% of the patients. Differences between patient groups (age, sex) were not statistically significant. Non-compliance with medication is one of the first things that need to be considered when a patient fails to respond to treatment. As it seems, primary non-compliance plays an important role. In further research, we would like to include more data about the patients’ treatment in the analysis and try to correlate this with their compliance.

Keywords: Key words: compliance, primary non-compliance, statins, adherence.

Published: January 1, 2006  Show citation