Klin Farmakol Farm. 2008;22(1):34-39

Sepsis in children

Olga Černá, Pavla Pokorná, Martin Sádlo
Klinika dětského a dorostového lékařství 1. LF UK a VFN, Praha

Sepsis is defined as an inflammatory mechanism by an organism in response to a pathogen. The controversies of sepsis in adults in comparison with sepsis in children are discussed in this paper. The fact that the clinical symptoms or laboratory parameters of sepsis do not exist. Definition and etiology of sepsis and SIRS (systemic inflammatory response syndrom) in children are different from that in adults. Sepsis therapy must be complete in consideration to MODS (multiple organ dysfunction syndrom) and other factors. We discussed basic facts in different therapies of sepsis in adults and children.

Keywords: Key words: definition of sepsis, SIRS, mortality, multiple organ dysfunction, therapy.

Published: April 1, 2008  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Černá O, Pokorná P, Sádlo M. Sepsis in children. Klin Farmakol Farm. 2008;22(1):34-39.
Download citation

References

  1. Bone RC, American College of Chest Physicians/Society of Critical Care Medicine, Consensus conference: Definitions for sepsis and organ failure and guidlines for the use of innovative therapies in sepsis. Critical Care Med. 1992; 20; 864-874. Go to original source... Go to PubMed...
  2. Goldstein B, Giroir B, Randolph A, and the Members of the International Consensus on Pediatric Sepsis. International pediatric sepsis consensus conference: Definition for sepsis and organ dysfunction in pediatrics. Pediatric Critical Care Med. 2005; 6(1): 2-8. Go to original source...
  3. Levy MM, Fink MP, Marshall JC et al. 2001 SCCM/ACCP/ATS/SIS International Sepsis Definitions Conference. Critical Care Med. 2003; 31(4): 1250-1256. Go to original source... Go to PubMed...
  4. Černý V, Novák I, Cvachovec K a kol. Sepse v intenzivní péči. Praha: Maxdorf 2002.
  5. Dellinger RP, Carlet JM, Masur H et al. Surviving sepsis Campaign guidelines for management of severe sepsis and septic shock, Critical Care Med. 2004; 32(3): 858 - 873. Go to original source... Go to PubMed...
  6. Závada J. Syndrom multiorgánové dysfunkce. Praha: Grada 2001.
  7. Parker MM, Hazelzet JA, Carcillo JA. Pediatric considerations, Critical Care Med. 2004; 32(11): 591-594. Go to original source... Go to PubMed...
  8. Fuhrman BP, Zimmerman JJ. Pediatric critical care. Mosby 2006.
  9. Taeusch HW, Ballard RA. Avery´s Disease of the Newborn. Saunders 1998.
  10. Taketomo CK, Hoddidng JH, Kraus DM et al. Pediatric Dosage Handbook. International Index 12 th Edition, Ohio 2005.
  11. Young TE, Mangum B. Neofax. Acorn Publishing, Inc 2002.
  12. Yaffe SJ, Aranda JV. Neonatal and Pediatric Pharmacology. Lippincott Williams & Wilkins 2005.
  13. Melendez E, Bachur R. Advances in the emergency management of Pediatric sepsis, Curr Opin Pediatr. 2006; 18: 245-253. Go to original source... Go to PubMed...
  14. Ben Jaballah N, Khaldi A et al. High-frequency oscillatory ventilation in pediatric patients with acute respiratory failure. Pediatr Crit Care Med. 2006; 7(4): 362-367. Go to original source... Go to PubMed...
  15. Timmons O. Infection in pediatric acute respiratory distress syndrome.Semin Pediatr Infect Dis. 2006; 17(2): 65-71. Go to original source... Go to PubMed...
  16. Volf GK, Grychtol B et al. Regional lung volume changes in children with acute respiratory distress syndrome during a derecruitment maneuver. Crit Care Med. 2007; 35(8): 1972-1978. Go to original source... Go to PubMed...




Clinical Pharmacology and Pharmacy

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.