Klin Farmakol Farm. 2009;23(4):171-173

Pharmacotherapy of pain

Marek Hakl¹, Pavel Ševčík²

¹ Anesteziologicko-resuscitační klinika, Centrum pro léčbu bolesti LF MU a FN u sv. Anny v Brně

² Klinika anestezie, resuscitace a intenzivní medicíny LF MU a FN Brno

Pain is a subjective unpleasant sensation. When acute, pain serves its fundamental protective function, alerting the body to possible

damage. Chronic pain, however, loses this very function and becomes a disease in itself. Pharmacotherapy is one of the most effective

therapeutic options. The main strategies for pain management are derived from the WHO three-step analgesic ladder or, more recently, the

„lift system“ has been used. Strong opioids play a major role in the treatment of intense pain. Strict rules have to be followed when these

opioids are commenced, used and discontinued. It is the only way to achieve the maximum therapeutic effect and minimize the risk of

developing adverse effects or psychic dependence.

Keywords: acute pain, chronic pain, treatment strategy, opioid treatment

Published: May 1, 2010  Show citation