Klin Farmakol Farm. 2012;26(1):43-48 [Interní Med. 2011; 13(6): 236-240]
To address the different underlying defects of pathology of type 2 diabetes, a combined therapy of oral antidiabetic agents is essential.
The development of new agents that affect insulin secretion, alpha cell dysfunction, hepatic glucose overproduction and slow down the
progression of beta cell failure, could be considered as an additional objective for the management of diabetes. The early and adequate
combination therapy could provide a long-term effect on good glycaemic control an reduce diabetic and cardiovascular complication
in type 2 diabetic patients.
Published: April 24, 2012 Show citation