Klin Farmakol Farm. 2015;29(4):153-155

Estimated glomerular filtration rate in adult patients

Tomáš Šálek
Department of Biomedical Sciences, Faculty of Medicine,
University of Ostrava and Department of Clinical Biochemistry, Krajská nemocnice T. Bati, a. s.

Glomerular filtration rate (GFR) is the most important parameter of kidney function. Knowledge of GFR is very important for dosing of

drugs excreted by kidneys. It may be useful for therapeutic drug monitoring (TDM). The reference method for measurement of GFR is

inulin clearance, but this method is not available in current routine clinical practice. Serum creatinine and cystatin C are available markers

in daily clinical practice. Estimated glomerular filtration rates (eGFR) from these markers are used. CKD-EPI equations are recommended

for calculation of eGFR in adult patients.

Keywords: creatinine, cystatin C, renal insufficiency chronic, kidney function tests, terapeutic drug monitoring

Published: January 1, 2016  Show citation

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Šálek T. Estimated glomerular filtration rate in adult patients. Klin Farmakol Farm. 2015;29(4):153-155.
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