Klin Farmakol Farm. 2016;30(4):28-30 | DOI: 10.36290/far.2016.032

Breast cancer a chronic disease? The Anti-HER2 therapy

Markéta Pospíšková, Milan Kohoutek
KOC KNTB a.s., Zlín

Advanced breast cancer is up on rare cases generally incurable disease. Thanks to new knowledge about the biology of tumors,
which have brought to the treatment of new therapeutic options, an significant extension of survival for this diagnosis. Mainly
inclusion of anti HER2 treatments (trastuzumab, pertuzumab, trastuzumab emtansin, lapatinib), thanks to which the OS in patients
with HER2 gene amplification extended up to 56 months. But it is still an incurable illnes sand must, in addition to the efforts to
extend survival, think mainly to improve or at least maintain the quality of life of the patients.

Keywords: breast cancer, HER2, targeted therapy, transtuzumab, lapatinib

Published: December 1, 2016  Show citation

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Pospíšková M, Kohoutek M. Breast cancer a chronic disease? The Anti-HER2 therapy. Klin Farmakol Farm. 2016;30(4):28-30. doi: 10.36290/far.2016.032.
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    References

    1. Tesařová P. Metastatický karcinom prsu - chronické onemocnění s dobrou kvalitou života. Breast Cancer News: 2014; 4(3): 3.
    2. Cardoso F, Costa A, et al. ESO-ESMO 2nd international consensus guidelinesfor advanced breast cancer (ABC2) Annals of Oncology. 2014: 1-18. doi:10.1093/annonc/mdu385. Go to original source... Go to PubMed...
    3. Büchler T, Čejková J. Přehled biologické léčby HER2-pozitivního metastatického karcinomu prsu. Klin Farmakol Farm 2015; 29(1): 8-12.

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