Klin Farmakol Farm. 2021;35(1):19-23

Importance of antiepileptic drugs interactions in routine clinical practice

Ivana Kacířová1, 2, Milan Grundmann1
1 Ústav klinické farmakologie, Lékařská fakulta, Ostravská univerzita, Ostrava
2 Oddělení klinické farmakologie, Ústav laboratorní medicíny, Fakultní nemocnice Ostrava

The propensity of drug-drug interactions in antiepileptic drugs is high. The outcome either may be beneficial, if the therapeutic potency of the drug is enhanced, or harmful if the interaction causes an increase in the adverse effects of the drug or if a reduction in efficacy occurs. It is difficult to predict the full extent of drug interactions because of the large interindividual variation between patients. Therapeutic drug monitoring has been used as a tool to optimize therapy regimens for individual patient with epilepsy.

Keywords: antiepileptic drugs, interaction, therapeutic drug monitoring.

Published: April 9, 2021  Show citation

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Kacířová I, Grundmann M. Importance of antiepileptic drugs interactions in routine clinical practice. Klin Farmakol Farm. 2021;35(1):19-23.
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