Klin Farmakol Farm. 2007;21(1):15-21
In male population aged 40–70 years erectile dysfunction occurs in 52 %. The pathological changes by Doppler examination can be found up 90 %, ED can be consider as risk indicator chromíc heart failure, cause of ED can be trauma or iatrogenic damane RRP, TURP. The therapy is not found up 90 % of male. The introduction of new oral therapies has completely changed the diagnostic and therapeutic approuch to ED. We can distinguish drugs with central (yohinbin, apomorphin) and peripheral effect – PDE-5 inhibitors (sildenafil, tadalafil, vardenafil). Oral pharmacotherapy is the first –line therapy. PDE-5 inhibitors are associated with high efficacy and safety.
Published: January 1, 2007 Show citation