Klin Farmakol Farm. 2010;24(3):117-120
Combinations of penicillins with beta-lactamase inhibitor: utilization and expenditures
- Ústav farmakologie Lékařské fakulty UP a FN Olomouc
in the Czech Republic in 1997–2008
The aim of this study was to measure the development of utilization and costs of potentiated penicillins (J01CR) in the Czech Republic in
1997–2008. Standard methods for Drug Utilization Review studies was used, the data being obtained from the State Institute for Drug
Control database. Although total antibiotic utilisation remains stable, utilization of penicillin combinations increased in the followed
period from 1.77 DID in 1997 to 4.33 DID in 2008. Costs of them were 18.8 % of total antibiotic expenditures in 1997, and raised to 25.6 %
in 2008. Utilization of potentiated penicillins makes one fifth of total national antibiotic utilization and one fourth of total antibiotic
expenditures, but this increase in utilization and expenditures does not cause parallel increase in total antibiotic utilization and costs.
Potentiated penicillins rather replace other antibiotics.
Keywords: antibiotics, utilization, expenditures, potentiated penicillins
Published: October 15, 2010 Show citation
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