Klin Farmakol Farm. 2012;26(2):102-105

News in pain therapy

Marek Hakl
Centrum pro léčbu bolesti, ARK, LF MU a FN u sv. Anny v Brně

News in the treatment of pain affect both the new active substances, as well as on new formulations, extensions of indications already

used substances and new strategies in the treatment of various types of pain. News with which we can meet in our ambulances are especially

new forms of topical medications for the treatment of peripheral neuropathic pain, new pain in the group of NSAIDs and a much

anticipated non-invasively administered fentanyl for treatment of breakthrough pain in cancer patients. According to the promises of

pharmaceutical companies would also have had this year and finally wait for new molecules in the group of strong opioids tapentadolu

(Palexia) and the combination of strong opioid oxycodone and naloxone (Targin). This combination of active substances retains excellent

analgesic effect of oxycodone and also prevents opioid-induced constipation. These days, however, these drugs are not available.

Keywords: lornoxicam, capsaicin, lidokainová patch, acute pain, breakthrough pain, fentanyl

Published: July 31, 2012  Show citation

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Hakl M. News in pain therapy. Klin Farmakol Farm. 2012;26(2):102-105.
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References

  1. Doležal T. Lornoxicam v léčbě akutní a chronické bolesti. Farmakoterapie, 2011; 7(4): 435-437.
  2. Yakhno N, Guekht A, Skoromets A, et al. Analgesic efficacy and safety of lornoxicam quick-release formulation compared with diclofenac potassium: randomised, double-blind trial in acute low back pain. Clin Drug Investig 2006; 26: 267-277. Go to original source... Go to PubMed...
  3. Caruso I, Montrone F, Boari L, et al. Lornoxicam versus diclofenac in rheumatoid arthritis: a double-blind, multicenter study. Adv Ther 1994; 11: 132-138.
  4. Bernstein RM, Frenzel W. A comparative study of 2 dosage regimens of lornoxicam and a standard dosage of naproxen in patients with rheumatoid arthritis. Eur J Clin Res 1995; 7: 259-273.
  5. Wasner G, Kleinert A, Binder A, et al. Postherpetic neuralgia: topical lidocaine is effective in nociceptor-deprived skin. J Neurol 2005; 252: 677-686. Go to original source... Go to PubMed...
  6. Baron, et al. 5% lidocaine medicated plaster versus pregabalin in post-herpetic neuralgia and diabetic polyneuropathy: an open-label, non-inferiority two-stage RCT study. Curr Med Res Opin 2009; 25(7): 1663-1676. Go to original source... Go to PubMed...
  7. SPC léku Qutenza.
  8. Kabelka L, Kozák J, Lejčko J, Sláma O. Doporučený postup pro léčbu průlomové bolesti. Bolest 2011; 14(Suppl 1).




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