Klin Farmakol Farm. 2016;30(2):32-37 | DOI: 10.36290/far.2016.017

Symptomatic treatment of gouty arthritis

Hana Ciferská¹, Lenka Petrů¹, Jan Vachek²

¹ Revmatologický ústav, Praha, a Revmatologická klinika 1. LF UK Praha

² Klinika nefrologie, Všeobecná fakultní nemocnice a 1. LF UK Praha

Gouty arthritis belongs to the group of crystal-induced arthropathies and is among the most common inflammatory joint diseases

that is often associated with a wide range of metabolic diseases. Timely diagnosis and initiation of adequate treatment reduces

the duration of gouty attack. The gold standard is articular puncture, if technically feasible, with analysis of the articular aspirate

with demonstration of sodium urate crystals. If this is not feasible, diagnosis can be made based on the ACR (American College

of Rheumatology) classification criteria that are a combination of clinical symptoms and paraclinical examinations. The treatment

of chronic gout is associated with both preventing acute exacerbations and affecting uric acid levels as well as an effort to prevent

or reduce the formation of tophi and development of renal injury.

Keywords: gout, hyperuricaemia, uric acid, allopurinol, febuxostat, non-steroid anti-inflammatory drugs, colchicine, biological therapy

Published: September 19, 2016  Show citation