Klin Farmakol Farm. 2019;33(1):25-27 | DOI: 10.36290/far.2019.003

Overview of ophthalmic dosage forms

Lukáš Láznička1, Zdeňka Šklubalová2
1 Nemocniční lékárna, Fakultní nemocnice Královské Vinohrady, Praha
2 Univerzita Karlova, Farmaceutická fakulta v Hradci Králové, Katedra farmaceutické technologie

For the treatment and prevention of ocular diseases, most patients are treated with conventional drug delivery formulations such as
eye drops or ointments. Their disadvantage is the low bioavailability of the drug and frequent application. The new trends in the development
of ophthalmic preparations include the use of modern excipients and dosage forms to achieve higher bioavailability of the
drug. However, only a few modern devices have come into common clinical practice while others are being investigated in clinical trials.

Keywords: ophthalmic preparations, bioavailability, dosage forms

Published: April 25, 2019  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Láznička L, Šklubalová Z. Overview of ophthalmic dosage forms. Klin Farmakol Farm. 2019;33(1):25-27. doi: 10.36290/far.2019.003.
Download citation

References

  1. Ministerstvo zdravotnictví ČR. Český lékopis 2017. Praha: Grada Publishing; 2017
  2. Šklubalová Z, Vraníková B. Oční přípravky: (ocularia, ophthalmica). Praha: Maxdorf, 2018. Jessenius.
  3. Baranowski P, Karolewicz B, Gajda M, Pluta J. Ophthalmic drug dosage forms: characterisation and research methods. ScientificWorldJournal. 2014; 2014: 861904. Go to original source... Go to PubMed...
  4. Yarangümeli A, Kural G. Are there any benefits of Betoptic S (betaxolol HCl ophthalmic suspension) over other beta-blockers in the treatment of glaucoma? Expert Opin Pharmacother. 2004; 5(5): 1071-1081. Go to original source... Go to PubMed...
  5. Mikro-verze AISLP-2019. Dostupné ke dni 3. 1. 2019. Souhrn SPC Ikervis.
  6. Lallemand F, Daull P, Benita S, Buggage R, Garrigue JS. Successfully improving ocular drug delivery using the cationic nanoemulsion, Novasorb. Journal of Drug Delivery. 2012. Go to original source... Go to PubMed...
  7. Ludvig A. The use of mucoadhesive polymers in ocular drug delivery. Adv. Drug Del. Rev. 2005; 57(11): 1595-1639. Go to original source... Go to PubMed...
  8. Gajdziok J, Vetchý D. Mukoadhezivní polymery v lékových formách. Chem Listy. 2012; 106: 632-638.
  9. Rah, MJ. A review of hyaluronan and its ophthalmic applications. Optometry - Journal of the American Optometric Association. 2011, 82(1): 38-43. Go to original source... Go to PubMed...
  10. Šklubalová Z. In situ gelující polymery pro oční kapky. Čes Slov Farm. 2005; 54(1): 4-10.
  11. Christian JF, Marlies G, van den Biggelaar JH, Nuijts RM. Topical drug delivery devices: A review. 2018; 168: 149-160.
  12. Nisha S, Deepak K. An insight to ophthalmic drug delivery system. International Journal of Pharmaceutical Studies Research. 2012; 3(2): 9-13.
  13. Rajasekaran A, Kumaran KSGA, Preetha JP, Karthika K. A comparative review on conventional and advanced ocular drug delivery formulations. International Journal of PharmTech Research. 2010; 2(1): 668-674.
  14. Ozurdex. Dostupné ke dni 3. 1. 2019 z: www.ozurdex.com
  15. Masteiková R. Aplikační systémy pro léčení onemocnění vnitřního oka. Prakt Lékáren. 2005; 1(2): 100-102.
  16. Mikro-verze AISLP-2019. Dostupné ke dni 5. 1. 2019. Souhrn SPC Mydrane inj sol.
  17. Mikro-verze AISLP-2019. Dostupné ke dni 5. 1. 2019. Souhrn SPC Aprokam 50 mg inj plv sol.
  18. Suchopár J, Valentová Š, ed. Compendium - léčiva používaná v podmínkách ČR. 5. vyd. Praha: Panax, 2018.
  19. Zimčík P, Miletín M. fotodynamická terapie jako nová perspektivní metoda léčby nádorových onemocnění II. Přehled fotosenzitizérů. Čes Slov Farm. 2004; 53(6): 271-279.
  20. Mikro-verze AISLP-2019. Dostupné ke dni 5. 1. 2019. Souhrn SPC Visudyne.
  21. Tangri P, Khurana S. Basics of ocular drug delivery systems. International Journal of Research in Pharmaceutical and Biomedical Sciences, 2011; 2(4): 1541-1552.




Clinical Pharmacology and Pharmacy

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.