Klin Farmakol Farm. 2022;36(3):115-117 | DOI: 10.36290/far.2022.019
Lercanidipine overdose
- 1 Ústav farmakologie Fakultní nemocnice Olomouc a Lékařské fakulty Univerzity Palackého v Olomouci
- 2 Ústav soudního lékařství a medicínského práva Fakultní nemocnice Olomouc a Lékařské fakulty Univerzity Palackého v Olomouci
- 3 II. interní klinika Fakultní nemocnice Olomouc, Lékařská fakulta Univerzity Palackého v Olomouci
The case report describes a case of poisoning with lercanidipine, a widely prescribed drug from the group of calcium channel blockers. It follows the case of a 31-year-old man who took 90-100 tablets, equivalent to 900-1000 mg, in a suicide attempt. This is the highest administered dose known yet. The patient was given a gastric lavage, administered activated charcoal and Fortrans (macrogol) to speed up drug elimination. Subsequently, CaCl2 was administered while ionized calcium levels were monitored. After 3 days in the ICU, the patient could be transferred to the psychiatric ward and discharged to home care after less than a week.
Keywords: lercanidipine overdose, calcium channel blockers, dihydropyridines.
Accepted: November 3, 2022; Published: November 3, 2022 Show citation
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